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Shimadzu Review 78[3・4] (2021)
Abstract
Genetic testing has spread rapidly in recent years, and the gene analysis techniques used to perform this genetic testing require nucleic acid extraction as a sample preparation step. Nucleic acid extraction based on the widely used spin column method requires complicated sample and reagent dispensing operations that not only take time and skill but also introduce the risk of contamination. This article briefly describes the development of the EluNA nucleic acid extraction system that offers quick and easy nucleic acid extraction without the need for an experienced user by utilizing hydrophobic gel to partition and isolate reagents and manipulating silica magnetic particles. With EluNA, nucleic acid extraction can be completed in just 10 minutes, or less than one-third the time of the conventional method, and the equipment occupies minimal benchtop space. The EluNA system promises to free users from complicated benchtop operations and transform the nucleic acid extraction workflow.
1Clinical & Biotechnology Business Unit, Life Science Business Department, Analytical & Measuring Instruments Division, Shimadzu Corporation, Kyoto, Japan
2Environmental Business Unit, Analytical & Measuring Instruments Division, Shimadzu Corporation, Kyoto, Japan
3Research & Development Department, Analytical & Measuring Instruments Division, Shimadzu Corporation, Kyoto, Japan
4Bio-Industry Unit, Technology Research Laboratory, Shimadzu Corporation, Kyoto, Japan
5Human Resources Department, Shimadzu Corporation, Kyoto, Japan
6Global Application Development Center, Analytical & Measuring Instruments Division, Shimadzu Corporation, Kyoto, Japan
*The information contained in Shimadzu Review has not been modified since the original publication date. Please be aware that in some cases, products mentioned within the articles are no longer available.