Shimadzu Review Vol.82[1・2](2025)
150 Years Anniversary Special Issue “Science and Technology that Contributes to Society”

SPECIALLY COLLECTED PAPERS

Simultaneous Analysis of 40 PFAS in Drinking Water

Nami IwasaYui HigashiRiki Kitano

Shimadzu Review 82[1・2] (2025)

Abstract

Perfluoroalkyl and polyfluoroalkyl substances (PFAS) offer broad versatility for a wide range of applications. Due to their structural stability and resistance to decomposition, they easily accumulate in the environment and are suspect-ed to be harmful for humans. Due to concerns about their environmental impacts, the U.S. Environmental Protection Agency (EPA) and the European Chemicals Agency (ECHA) have been implementing measures to strengthen PFAS-related regulations in recent years. Consequently, efforts to comply with such PFAS regulations have been increasing every year and the list of compounds governed by such regulations continues to grow. That makes it increasingly useful to establish an analytical method that can reliably analyze all the various PFAS at the same time.  
This article describes research that established an LC/MS/MS analytical method for simultaneously analyzing 40 PFAS as target compounds in drinking water and verified the utility and accuracy of the method based on spike-and-recovery tests of the drinking water samples and a standard sample.


Solutions COE, Analytical & Measuring Instruments Division, Shimadzu Corporation, Kyoto, Japan

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