Monitoring Dimethylacetamide in complex water matrix using GC-MS/MS (MRM)


User Benefits

- GCMS-TQ8050 NX offers advanced capabilities for the detection of DMAc in water sample. - Superior reliability and reproducibility demonstrated. - High sensitivity and selectivity when using MRM for detecting and quantitating DMAc. - The proposed sample preparation steps successfully cleaned up water ample with complex matrices for GCMS analysis.


As a result, DMAc might be discharged accidentally or illegally to nearby water bodies, hence contaminating freshwater bodies that are meant to produce portable drinking water. DMAc was added to the list of substances of very high concern (SVHC) by EU in 2011 due to its toxicity effect observed on the reproduction system. A study conducted on rats demonstrated that at 400 mg/kg bw/day, DMAc was capable of causing damage to the fetus's development. In addition, DMAc was also known to cause liver damage. In summary, the discharge from industries to the environment, and water bodies near industrial areas should be closely monitored for DMAc to safeguard public health. In this application news, the capability of Shimadzu GCMS-TQ8050 NX will be demonstrated to detect and quantify DMAc in water samples. The methodology proposed is easily deployed by testing labs, on a wide variety of water sample matrices using generic apparatus that are commonly available. Making use the superior sensitivity of GCMS-TQ8050 NX, the consuming step of concentrating the sample after liquid-liquid extraction can be skipped.

March 20, 2024 GMT

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