High-Sensitivity Analysis of Nonylphenol in River Water Using GC-MS/MS

Nonylphenol (NP) is used as a raw material for the production of surfactants, and as an antioxidant used to protect rubber and plastics, etc. However, in recent years, it has been specified as a substance that can cause endocrine disruption in the environment (environmental hormone). We investigated the use of a high m/z selectivity triple quadrupole gas chromatograph-mass spectrometer (GC-MS/MS) in the analysis of NP in river water, which typically contains many contaminants. Analysis was possible without adversely affecting identification accuracy, even when omitting the cleanup procedure that may reduce the recovery rate.