MALDI-MS Protein Profiling of Chemoresistance in Extracellular Vesicles of Cancer Cells
Cancer cells could be divided into groups by differences in chemoresistance by profiling the differential expression of proteins in extracellular vesicles (EV) as a result of an increase in the chemoresistance of cancer cells using a system combining a MALDI-8020 benchtop MALDI-TOF MS and the statistical analysis software eMSTAT Solution. In the future, the MALDI-TOF MS protein profiling approach is expected to be useful as a novel tool for minimally invasive cancer diagnostics and chemotherapy monitoring, for example, for early detection of therapy resistance without biopsy.
- Content Type:
- Application
- Document Number:
- LAAN-A-TM-E067
- Product Type:
- Mass Spectrometry, Life Science Lab Instruments, MALDI-TOF Mass Spectrometry
- Keywords:
- Protein profiling, chemoresistance, extracellular vesicle, cancer cell, fluorouracil, eMSTAT Solution, Clinical research, Forensics, Pharmaceutical, Life Science, Forensics, Toxicology, Drug test, Clinical research, MALDI-8020
- Language:
- English
- File Name:
- jpo319048.pdf
- File Size:
- 335kb
