Application Highlights

In the process of analytical method development using MALDI, the choice of matrix, ratios of solvents and data acquisition strategies are critical components to achieve optimum signal. Whilst many of the initial stages in method development will relate to the molecular size and chemical nature of the analyte, optimisation of sample preparation and acquisition parameters is necessary to achieve the optimal analytical method for your analyte of interest. MALDI mass spectrometry imaging (MALDI-MSI) is a useful tool to better understand the distribution of analyte to matrix within the spot to assess homogeneity of the preparation. It also provides information to actively determine the optimal acquisition settings (e.g. raster pattern) to achieve both the best signal to noise ratio and reduce spot to spot variation to give more consistent results.

FTIR TALK LETTER is a booklet focused on Fourier transform infrared spectroscopy. It contains a wide range of information, from the latest topics to analytical techniques and fundamentals of FTIR. We interview experts from various fields, sharing their experiences and opinions on FTIR and related instruments.
INDEX
・ Identification and Quantitation of Microscopic Elastomer Particles and Tire and Road Wear Particles (TRWPs) in Sediment Using a FTIR Microscopy Method
・ The IRSpirit-ZX FTIR Spectrophotometer
・Notes on Infrared Spectral Analysis – Carbonyls (Part 2) –