Automated Scale-up from Analytical to Preparative LC/MS to accelerate compound purification and isolation

A unique algorithm for compound isolation and purification

ASAPrep initially verifies the retention time of the target compound using the analytical-scale LC data. The retention time of the target compound is then used by the ASAPrep algorithm to calculate the focused gradient profile for the preparative-scale separation to deliver the highest purity and recovery of the collected LC fractions.

In the example shown below, the ASAPrep algorithm has been used to change the retention time of each target compound in the preparative scale separation to elute at ~4.3 minutes.

Modifying the preparative scale focused gradient profile for each target compound to an elution time of ~4.3 minutes using L-Column ODS 2

For Research Use Only. Not for use in diagnostic procedures.

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