DPiMS™-8060 Method Package for Rapid Toxicology Screening

Simple pretreatment for blood samples with only dilution and centrifugation needed

With the DPiMS-8060, time-consuming pretreatment steps associated with forensic samples are almost completely eliminated. Begin analysis after only simple dilution and centrifugation steps. The DPiMS-8060 is therefore extremely well-suited for mass analysis via rapid screening.

 

Screening of 64 toxic substances in just 3 minutes

This method package provides MRM simultaneous analysis methods for approx. 64 compounds often seen in forensic cases including illicit drugs, narcotics, psychotropics and medical drugs.

 

Ready-to-use method

When using this method package with the DPiMS-8060 for mass analysis, it is no longer necessary to spend time and effort considering analysis conditions or optimizing MS parameters for each compound before starting the analysis. The simultaneous analysis of several compounds can be carried out much more efficiently.

 

Support for easy quantitation from pretreatment to data processing

For each compound in the method package, calibration curve information for internal standards is listed, enabling easy quantitation post-analysis.

 

Easily change units for LC-MS/MS analysis

DPiMS-8060 is an optional ionization kit for the LCMS-8045/8050/8060. It is simple for users to change units to an ESI unit for LC-MS/MS analysis. For example, change between interfaces to quickly check whether a compound has been detected with DPiMS or carry out LC-MS/MS analysis including detailed quantitation.

 

Software that prioritizes simplicity

PESI MS Solution is dedicated software which allows the user to begin analysis by simply selecting the method, setting the sample in place, and pressing the start button. Once analysis is complete, it is easy to create a report file showing the presence or absence of the target compounds.

 

Compounds in the database

Abused drugs etc. Narcotics, psychotropics etc. Antipsychotics etc.
Acetyl Fentanyl
Cocaine
Dihydrocodeine
Diphenidine
MDA
MDMA
Methamphetamine
Morphine
Alprazolam
Bromazepam
Brotizolam
Clobazam
Clotiazepam
Cloxazolam
Diazepam
Diphenhydramine
Estazolam
Etizolam
Fludiazepam
Flunitrazepam
Flurazepam
Medazepam
Midazolam
Nitrazepam
Pemoline
Prazepam
Quazepam
Triazolam
Zolpidem
Amitriptyline
Amoxapine
Blonanserin
Carpipramine
Chlorpromazine
Clocapramine
Clomipramine
Clozapine
Desipramine
Dosulepin
Duloxetine
Escitalopram
Fluvoxamine
Levomepromazine
Maprotiline
Mianserin
Mirtazapine
Nortriptyline
Perphenazine
Pimozide
Promethazine
Propericiazine
Quetiapine
Risperidone
Sulpiride
Tandospirone
Trazodone
Zotepine
Other compounds
Atropine
Bupivacaine
Carbamazepine
Colchicine
Lidocaine
Sildenafil
Tofisopam

Cautions

  1. Concentrations calculated with this method package are approximate values, and may differ significantly from true values depending on the samples used and the condition of the equipment. Such values should not form the basis for legal or medical decisions. In order to obtain accurate quantitative values, a quantitative method using calibration curves from standard samples is required.
  2. Shimadzu provides no guarantee with regards to the accuracy of information included in the database or the usefulness of information obtained using the database.
  3. Appropriate quality control tests should be carried out using standard samples to confirm qualitative information obtained with this method package.

DPiMS is a trademark of Shimadzu Corporation.

For Research Use Only. Not for use in diagnostic procedures.

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