LCMS Food Safety Application is now available.
Trap-Free 2D LC/MS system for Quadrupole LCMS
Enhancing the Efficiency of Impurity Analysis
When impurities are detected by UV under non-volatile mobile phase conditions, does one need to adapt the method to use volatile mobile phase additives for LCMS confirmation?
With the use of a Trap-free 2D LCMS system, no additional method development is required because mobile phases can be changed online.
- Online switching between a non-volatile mobile phase and a volatile mobile phase
- Convenient support tool coordinated within LabSolutions
- Only the impurities of interest are introduced to the MS system, so there are no concerns about peak misalignment.
Creating a Time Program and Batch Schedule using the Support Tool
The optimal valve sequence can be constructed by entering the retention times for impurity peaks observed in the first-dimension UV chromatogram, and then a batch schedule can be created to acquire data on multiple impurities and their respective blanks.
Using the Data Browser Makes Identification of Impurities Easy
Remarks and Precautions
- The Trap-Free 2D LCMS System is a application system and is configured with LC units, Quadrupole mass spectrometer, and start kit
News / Events
Application Note: "Analysis of Pharmaceuticals' Impurity - Regulations and Analysis for Carcinogenic Substances -"
Application Note: "Various Analysis Techniques for Organic Acids and Examples of Their Application"
Shimadzu has released the Metabolites Method Package Suite.
Provides ready-to-use methods for over 1900 metabolites
This suite allows comprehensive analysis of over 1900 metabolites without the need for investigation of separation conditions, MRM optimization or parameter settings.
Direct Probe Ionization Mass Spectrometer - APPLICATION NOTEBOOK -
Shimadzu has released the LC/MS/MS Rapid Toxicology Screening System Ver.3.
This system improves the efficiency of simultaneous LC/MS/MS analysis methods by allowing the user to start analysis without time-consuming steps such as consideration of separation conditions and MS parameter optimization.