Co-Sense for BA (Bio-sample Analysis) - Features

Liquid Chromatograph with online Sample Preparation

Adoption of an On-line Dilution Bypass

Co-Sense for BA features the dilution bypass added in the sample introduction flow channel leading to the pretreatment column. Use of a buffer solution as the sample introduction mobile phase or adding a small amount of organic solvent to it ensures effective trapping and concentration of even drugs with a high rate of protein binding, leading to highly efficient deproteinization and a high recovery rate. Thus, direct injection of unprocessed blood plasma or blood serum has become possible.

Temperature Control Encompasses the Pretreatment Column

Since the high pressure flow channel switching valve is placed inside the column oven, the temperature of the pretreatment column can be controlled accurately. Control of the pretreatment column temperature assures consistently high recovery rate and accurate analysis.

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