Pharmaceutical Excipient Identification Test Using IR Pilot™

Introduction

The Shimadzu IRSpirit is a compact FTIR with a footprint approximately the size of an A3 (11 × 17 in) sheet of paper. Designed to take up little space, the sample compartment of the IRSpirit is easily accessible whether installed in “landscape” or “portrait” orientation, so that even a narrow opening on a lab bench can accommodate it. The performance it provides is remarkable too, with the highest signal to noise ratio and maximum resolution in its class. These high-level specifications translate into robust results, especially considering its small footprint. Shimadzu realizes that customers need access to a wide variety of sampling accessories to get the most out of their FTIR. The sampling compartment of the IRSpirit is designed for maximum flexibility, and accommodates existing Shimadzu and third party accessories such as ATR and diffuse reflectance, as well as transmission accessories such as a KBr pellet holder and demountable cells. Software ease of use is almost as important as its functionality. IR Pilot, an analyzer interface within LabSolutions IR, had four common workflows by default: chemical identification, contaminant analysis, quantitative analysis, and film thickness determination. User determined workflows can be created and saved as well. With push-button simplicity, the user selects an analysis, chooses a method and corresponding accessory, picks relevant data manipulation steps, and then starts the measurement. After data collection, a report is created, summarizing data collection parameters and providing interpreted results. This article highlights the features of the IRSpirit, focusing on the Identification Test workflow.

June 1, 2018 GMT