Direct Analysis of Glyphosate, Glufosinate and AMPA in Foods Using a Triple Quadrupole C210 LC/MS/MS

Introduction

Glufosinate and glyphosate are non-selective herbicides used for various purposes in both the agricultural and domestic sectors. For grains, in particular, they are used as pre-harvest herbicides to reduce the work needed for harvesting, and the maximum residue limits has been established by country or regions. When degraded in soil and water, glyphosate produces aminomethylphosphonic acid (AMPA) as a metabolite. Glyphosate, glufosinate and AMPA are all highly polar compounds, making retention in the reversed-phase mode with HPLC or LC-MS difficult. Therefore, analysis usually employs derivatization using FMOC. The C181 issue of Application News introduced a method which allows direct analysis of glyphosate, glufosinate and AMPA in beverages without derivatization . This article reports a direct analysis for food samples, such as grains and fruits, pretreated using the QuPPe (Quick Polar Pesticides) method developed by EURL (Stuttgart, Germany).

June 26, 2020 GMT