Simultaneous Analysis of 16 Sweeteners Using Triple Quadrupole LC/MS/MS [LCMS-8050]

Liquid Chromatography Mass Spectrometry

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Introduction

Artificial sweeteners such as aspartame, sucralose, and acesulfame potassium fall under the category of designated additives according to Japan's Food Sanitation Act, and prescribed standards are in place for their use in some foods and quantities. Cyclamate and other artificial sweeteners used in some regions outside Japan are included among undesignated additives in Japan, and inspection is required in specific imported foods. Consequently, quantitation for large numbers of sweeteners, including not only permitted in Japan but also undesignated, are needed. Application News C121 described the simultaneous analysis of nine artificial sweeteners including both designated and undesignated additives using an LCMS-8040 triple quadrupole LC/MS/MS system. In this article, we introduce an example of simultaneous analysis of 16 sweeteners using an LCMS-8050.

August 26, 2016 GMT