Nexera Mikros
Microflow LC-MS/MS Analysis of Monoclonal Antibody in Human Plasma at ng/mL Level with nSMOLTM Proteolysis
Microflow Liquid Chromatography Mass Spectrometry System
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Introduction
nSMOL proteolysis has been reported as the novel technology to standardize the sample preparation workflow and to improve the sensitivity of mass spectrometric assay of therapeutic monoclonal antibodies in human serum or plasma. We developed highly sensitive bioanalysis method to achieve low ng/ml sensitivity of Trastuzumab in human plasma with the combination of the nSMOL proteolysis and the newly developed Nexera MikrosTMy system.
October 1, 2018 GMT
