Simultaneous Analysis of Immunosuppressive and Antifungal Drugs in Human Blood Plasma Using LC/MS/MS (C 196)

Introduction

Mycophenolate mofetil, a prodrug for immunosuppressive drugs, is used to suppress rejection after organ transplantation. In addition, Voriconazole and Itraconazole are administered in combination as antifungal drugs to prevent infection after transplantation. This article introduces a simultaneous analysis of an immunosuppressive drug (mycophenolic acid), antifungal drugs (Voriconazole and Itraconazole) and metabolites using the LCMS^TM-8050 triple quadrupole high-performance liquid chromatograph mass spectrometer.

October 11, 2019 GMT