Analysis of 1, 4-Dioxane in Water using GC/MS

Introduction

1,4-dioxane is used in various types of industrial solvents, such as lacquer, resin, paint remover, etc. When high concentration vapors are inhaled, acutely toxic symptoms, such as dizziness and nausea, occur. Further, it has been learned from recent animal test that long-term oral ingestion of low concentrations of 1,4-dioxane generates toxic and carcinogenic effects. 1,4-dioxane is highly soluble in water, and there is concern that its discharge in waste water and waste fumes causes a risk to the environment and to health. Accordingly, the Ministry of Health, Labor and Welfare of Japan fixed the criteria level for 1,4-dioxane in tap water at 0.05mg/L in the revision for the Drinking Water Test Method announced in 2003. This Application News introduces one of the analysis example of the determination of 1,4-dioxane using solid phase extraction GC/MS.

March 29, 2004 GMT