LCMS-TQ RX Series Triple Quadrupole LC-MS/MS
High Sensitivity Analysis of Testosterone in Human Serum Using LCMS™-8060NX
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Introduction
This report introduces an example of high sensitivity analysis of testosterone in serum using LCMS8060NX, a triple quadrupole mass spectrometer. Calibration curves prepared using standard samples showed linearity in the concentration range of 0.05 - 1000 pg/mL (R2 =0.9996), with %RSD of concentration of 2.47% at the lower limit of quantification and accuracy at each calibration point ranged from 94.64 - 111.04%. Furthermore, the accuracy of serum samples spiked with testosterone (1 pg/mL) was 105%, indicating that the method used in the analysis is suitable for the actual samples.
October 22, 2020 GMT
