Complementary bioimaging of Gadofluorine P in myocardial infarction in mice

Introduction

Magnetic resonance imaging (MRI) is a widely used imaging technique in the daily clinical practice. To enhance the contrast during this examination, several different contrast agents are available. Because of their excellent paramagnetic properties due to five or seven unpaired electrons, Fe3+ , Mn2+ or Gd3+ are mostly used. Since Gd3+ is toxic in the free form, this probe is administered as a complex with aminocarboxylic acids. While the most gadolinium-based contrast agents (GBCAs) distribute systemically, some target specific GBCAs are under investigation as well.

October 27, 2020 GMT