Qualitative Screening of Drugs in Whole Blood by DPiMS QT installed LCMS-9030

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User Benefits

- Screening of drugs in biological samples is possible with simple sample preparation. - Separation using a column is not necessary, and a comprehensive qualitative analysis can be conducted in a measurement time of 3 min. - iDIA which has narrower m/z window, and makes it possible to comprehensively acquire MS/MS spectra.

Introduction

A simpler and faster technique for identification of the relevant drugs in acquired samples has been required in analyses of drugs and poisons in forensic medicine and scientific criminal investigations. This Application News introduces a new analysis technique combining the DPiMS QT which is a probe kit of electrospray ionization unit and an LCMS-9030 quadrupole time-of-flight mass spectrometer for screening of drugs in human whole blood. The DPiMS QT makes it possible to conduct direct analysis and minimize the time required from sample preparation to analysis. Use of the newly-developed iDIA measurement method makes it possible to comprehensively acquire MS/MS spectra for all ionized compounds.

September 24, 2021 GMT