SIM and MRM Analysis of 3-MCPD, 3-MCPD Fatty Acid Esters, and Glycidol Fatty Acid Esters in Powdered Milk

User Benefits

- 3-MCPD, 3-MCPD fatty acid esters, and glycidol fatty acid esters can all be analyzed from a single sample. - MRM mode is less susceptible to contaminants and gives a more selective analysis. - The robustness of GCMS-TQ8050 NX enables highly sensitive MRM analysis with reliable results.

Introduction

Monochloropropanediols (MCPDs) are compounds that can potentially be generated from oils during food processing. Oils are also known to contain MCPD fatty acid esters, which are MCPDs bound to fatty acids, and glycidol fatty acid esters that form 3-MCPD in the body. In many countries, efforts are underway to reduce MCPD fatty acid esters and glycidol fatty acid esters in food due to concerns over health hazards. The European Food Safety Agency (EFSA) will also consider setting stricter standards for 3-MPCD fatty acid ester levels in infant milk formula during the 2 years commencing January 1, 2021. This study used GCMS-TQ8050 NX to perform SIM and MRM analysis of 3-MCPD, 3-MCPD fatty acid esters, and glycidol fatty acid esters in powdered milk. Samples were prepared based on AOAC Official Method 2018.12, which has been adopted as an analytical method by the EFSA.

February 3, 2022 GMT