Analysis of Negatively Charged Polymers using the MALDI-8030 Dual Polarity Benchtop MALDI-TOF Mass Spectrometer

User Benefits

- Easy polymer data analysis on affordable benchtop MALDI-8030 with good isotopic resolution - Data compatibility with Polymerix software produces confident results for polymer confirmation, indices and end-groups - MALDI-8030 with Polymerix is appropriate solution for polymer chemists and synthesis laboratories using negative mode

Introduction

The MALDI-8030 is the latest benchtop MALDI-TOF mass spectrometer from Shimadzu, building on the performance of the compact and powerful MALDI-8020. The MALDI-8030 offers the versatility to analyse samples in both positive and negative ion modes. In this article, we demonstrate the capability of the MALDI-8030 for the analysis of polymers that can not be easily analysed in positive ion mode. Polymethacrylic acid (PMAA) is a polymer with applications in tissue culture as a polymer conjugate, in chemotherapy as a nanoparticle drug delivery system and in the colourant industry as a controlled release capsule for dyes. The ability to analyse this polymer using MALDI allows for rapid characterisation and confirmation of synthesis products for busy laboratories.

April 5, 2022 GMT