Screening Analysis of Steroid Profiles and Qualitative Doping Substances by GC-MS/MS

Introduction

WADA-accredited laboratories around the world pursue to fight against doping in sports. Shimadzu GCMS-TQ^TM 8050 NX was selected as an instrument of choice for an anti-doping testing at international sports games held in 2021. The method developed for the games analyzed 180 substances, encompassing both quantitative and qualitative substances with one injection. The sensitivity, the linearity, and the robustness of the instrument were demonstrated with endogenous steroids quantified for steroid profiling. The sensitivity in qualitative analysis of target substances was also proved to be sufficient, and chromatograms were provided for a dozen of such substances as an illustration in this article. A document on the rest of the data is available specifically for those working in the WADA-accredited doping control laboratories. The readers interested in the document are encouraged to contact Shimadzu Corporation, or its oversea branches.

June 28, 2022 GMT