Determination of Trace Elements in Whole Blood by ICP-MS with Simple Dilution of Samples

User Benefits

- Whole blood samples are directly diluted and tested to avoid contamination and losses caused by complex pretreatment processes, while saving labor and time costs. - Low sample consumption enables simultaneous analysis of trace elements in batch samples for research.

Introduction

Elements are crucial substances that sustain normal metabolism and life activities within the human body. They serve as components of certain enzymes, hormones, and so on in the body and are also significant indicators of human nutritional status. Blood is a common biological fluid, a complex liquid mixture mainly composed of water, proteins, glucose, mineral salts, and red and white blood cells. Meanwhile, blood samples for research are characterized by small size yet large in quantity. Therefore, how to rapidly, accurately, and simply detect the content of multiple trace elements in bulk whole blood is an urgent problem that needs to be solved. This article uses a mixed dilution solution of 0.2 % HNO3+0.1 mg/L Au to dilute whole blood samples 20 times, and directly determines the content of 19 elements including Fe, Ca, Mg, Se, Hg, Pb in the samples by ICPMS-2050.

July 8, 2025 GMT