Analysis of the Degree of Coloration of Liquids Compliant to European Pharmacopeia

User Benefits

- Semi-Automated analysis with LabSolutions UV-Vis and Multi Data Report. - Fully Part 11 CFR compliant through use of audit trail and electronic signatures for raw data and report. - Highly customizable to fit any corporate identity, SOP or other applicable documents.

Introduction

Chapter 2.2.2. Degree of Coloration of Liquids of the European Pharmacopeia (short EP in the following text) specifies how to determine the coloration of a liquid sample, which is an important criterion in pharmaceutical quality control. By definition, a liquid is colorless if it has the appearance of water or the solvent used in its preparation. Several reference solutions are specified in this chapter, which are created from mixing yellow, red and blue primary solutions. In the past, each of these solutions was compared visually to a sample. Since EP 10.3, using a spectrophotometer and software-based analysis is allowed as alternative to this traditional method. In this application, a semi-automated approach is shown that uses LabSolutions UV-Vis Color analysis software and the LabSolutions Multi Data Report to assign the correct color number to a sample. This solution significantly reduces the number of manual steps and allows full traceability of the data via audit trail and electronic signatures for raw data, templates and finished reports.

January 22, 2026 GMT