Smart Metabolites Database
Database Software for GC/MS and GC-MS/MS Analysis of Metabolites
The Smart Metabolites Database is the world’s only commercial database for GC-MS/MS analysis of metabolomics. It enables MRM method development using the Shimadzu GCMS-TQ series instruments. Biological samples can contain many metabolites along with complex matrices, making it difficult to identify and measure the target compounds using traditional techniques. However, the triple quadrupole Multiple Reaction Monitoring (MRM) acquisition mode performs the mass separation twice, eliminating matrix interference and enabling detection and quantitation of components that could not otherwise be analyzed by conventional Scan or SIM acquisition modes.
The Smart Metabolites Database package includes acquisition methods with fully optimized GC parameters for each compound. The database includes retention indices (RI) for predictive calculation of compound retention times (RT).
By simply selecting the compounds to be measured from among those registered in the database, the MRM or Scan/MRM acquisition method is created automatically.
This database was developed through guidance from the Shimane University Faculty of Medicine, Kobe University School of Medicine, and the Institute for Integrated Cell-Material Sciences, Kyoto University. Part of this database was obtained as a result of development work related to the project for "Development of fundamental technologies for promoting industrial application of human stem cells and development of fundamental evaluation technologies for practical application of human stem cells" commissioned by Japan's New Energy and Industrial Technology Development Organization (NEDO).