When analyzing mass spectra, first molecular ions...
GC/MS CI , CI/NCI and SMCI Measurement

CI is a softer ionization method than EI, fragmentation is less likely to occur, so molecular weight information is more readily obtained. Negative chemical ionization (NCI) or negative ion chemical ionization (NICI) enables selectively measuring, with ultra high sensitivity, chemical substances with an electron affinity, such as chlorine-based compounds.
Features
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Since information about molecular weight can be obtained easily using chemical ionization (CI), accurate qualification is possible.
When analyzing mass spectra, first molecular ions... -
Negative chemical ionization (NCI) or negative ion chemical ionization (NICI) enables selectively measuring, with ultra high sensitivity, chemical substances with an electron affinity, such as chlorine-based compounds...
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SMCI stands for Solvent Mediated Chemical Ionization, a soft ionization method for GCMS. The headspace reagent gas from the sample bottle is introduced into the GCMS ionization unit to be...
News / Events
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Shimadzu at ASMS 2023
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Life Science Biomarker Industry Page has been updated
Biomarkers are derived from living organisms and found in tissues, blood, and other bodily fluids. Biomarkers are indicators of biological changes in an organism and are used to diagnose disease, in prognosis, and to evaluate the efficacy and safety of pharmaceuticals. Biomarkers can be nucleic acids, proteins, peptides, lipids, and sugars, and are identified using various “omics” techniques.
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Life Science Proteomics Industry Page has been updated
Proteomics is an academic discipline involving the comprehensive study of protein structure and function, typically by mass spectrometry and electrophoresis. Unlike the genome, the cells of an organism do not all contain the same complement of proteins, but different cells contain different proteins at different times. Proteomics uses this phenomenon to enable more efficient drug development and to determine the mechanisms of disease.
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Sports doping
Anti-doping policies, rules and regulations are governed by the World Anti-Doping Agency (WADA). Doping is not only harmful to athletes who take performance-boosting drugs, but also affects the integrity of a sport. Shimadzu instruments can help ensure clean sports and here are a few applications.
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Shimadzu has released Peakintelligence™ for GCMS
Peakintelligence for GCMS is equipped with new AI peak integration algorithms that significantly shorten the time needed for peak integration in the GC/MS/MS quantitative processing work sequence. AI algorithms trained with peak integration know-how provide peak integration on par with that of an experienced user, so configuring or adjusting parameters is not required. In addition, the software can correctly detect low-concentration samples.
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What is a Method Package?
Method Package contains ready-to-use analytical conditions and sample pretreatment procedures optimized for Shimadzu mass spectrometers and specific analytical applications.