Forensic Toxicology Database for LC-MS/MS
LC/MS/MS Forensic Toxicology Database
For LabSolutions™ LCMS
The database includes information on drugs of abuse, hypnotics, psychotropics, pesticides, prescription drugs and natural toxins.
Simplified Acquisition and Identification
The Forensic Toxicology Database includes optimized LC-MS/MS data acquisition parameters and a library database to help clinical and forensic researchers build screening and quantitation methods quickly, simplifying method development.
MRM & Spectral Library database contains information on more than 2,500 compounds
The spectral library database is built using two separation conditions (ODS and Biphenyl). Both methods have information on clinical and forensic compounds of interest in routine analysis. The ODS method contains information on 1,250 compounds and the Biphenyl method contains 1,281 compounds. Compound datasheet includes: monoisotopic mass, RT, CAS number, formula and compound class. This package provides Synchronized Survey Scan parameters (MRM parameters, MRM intensity threshold and triggered product ion scan parameters) optimized for screening analysis.
Enhanced identification by merged spectrum
Each certified reference material was acquired with three different collision energies to generate an information-rich merged-CE spectrum which can be used in library matching and compound verification. Matching with a merged-CE spectrum library can be a powerful tool to identify compounds with a library score.
Method Creation by “Compound List Creation Tool”
Compound Identification by Merged Spectra
Analytical Conditions for ODS column
|Phenomenex Kinetex XB-C18 (2.1 mmI.D. x 100 mmL., 2.6um)
Phenomenex SecurityGuard ULTRA C18 2.1mmID
|Mobile phase A
10 mmol/L ammonium formate + 0.1% formic acid – water
|Mobile phase B
|10 mmol/L ammonium formate + 0.1% formic acid – methanol
|0.3 mL / min
Analytical Conditions for Biphenyl column
|Restek Raptor Biphenyl (2.1 mmI.D. x 100 mmL., 2.7um)
|Mobile phase A
2 mmol/L ammonium formate + 0.002% formic acid – water
|Mobile phase B
|2 mmol/L ammonium formate + 0.002% formic acid – methanol
0.3 mL/min (0.5 mL/min from 11 min to 14 min)
Remarks and Precautions
- LabSolutions LCMS Ver. 5.109 or later and LabSolutions Insight Ver. 3.8SP1 or later are required.
- It is the user’s responsibility to adopt appropriate quality control tests using standard samples to confirm qualitative and quantitative information obtained with the database.
LabSolutions is a trademark of Shimadzu Corporation or its affiliated companies in Japan and/or other countries.
For Research Use Only. Not for use in diagnostic procedures.
News / Events
OAD-TOF system Interview with Dr.Hiroshi Tsugawa
The OAD-TOF system is a Q-TOF LCMS that realizes OAD (Oxygen Attachment Dissociation), Shimadzu's proprietary fragmentation technology. It allows the analysis of the position of carbon-carbon double bonds in lipids and other organic compounds. Combined with the LCMS -9050, which boasts world-class high mass accuracy and fast polarity switching, it enables the creation of innovative applications.
Metabolic Pathway Analysis Solutions
Metabolic pathways are the chain of chemical and enzymatic reactions that occur within a cell in living organisms to support their life.
AOAC INTERNATIONAL Posters are now available.
Shimadzu has released the OAD-TOF system
The OAD-TOF system is a Q-TOF LCMS that realizes OAD (Oxygen Attachment Dissociation), Shimadzu's proprietary fragmentation technology. It allows the analysis of the position of carbon-carbon double bonds in lipids and other organic compounds. Combined with the LCMS-9050, which boasts world-class high mass accuracy and fast polarity switching, it enables the creation of innovative applications.
Shimadzu has released the LC/MS/MS Method Package for Sugars and Sugar Nucle
The LC/MS/MS Method Package for Sugars and Sugar Nucleotides includes LC/MS/MS analytical methods with analytical conditions and MS parameter settings optimized for analyzing 25 different sugars, amino sugars, sugar acids and sugar alcohols, 9 different sugar nucleotides, related metabolites, and internal standards.
Latest issue of Shimadzu Journal, featuring Forensics / Toxicology, has come out.
This issue focuses on "Forensics / Toxicology", an area where science and technology are particularly important and needed. It starts with two customer interviews.