LC/MS/MS Method Package for Mycotoxins
For LabSolutions™ LCMS
Mycotoxins are highly toxic chemical byproducts from fungi commonly found in crops, and residual content in foods are regulated the world over. This method package provides simultaneous multi-component analysis conditions for mycotoxins subject to the regulations in Japan, the USA, the EU, and China.
Analytical Methods for 27 Mycotoxins
This package contains seven different analytical method conditions and fully optimized MRM transitions for a total of 27 different mycotoxins. Rapid analytical methods are included for a 25 mycotoxin screen, 16 mycotoxins using high-sensitivity conditions, 10 mycotoxins using APCI, and specialized methods for trichothecenes, fumonisins, aflatoxins, and patulin.
Description of Each Method
| Outline | Analysis time | Description | |
|---|---|---|---|
| A | Rapid analysis method for 25 components | 20 min | This method rapidly and simultaneously analyzes 25 Mycotoxins. Carryovers are minimized by adopting the rinsing function from the Nexera series. |
| B | High-sensitivity analysis method for 16 components | 30 min | This method analyzes trichothecene mycotoxins with high sensitivity. |
| C | Method for analysis of patulin | 10 min | This method analyzes patulin. |
| D | Method for analysis of aflatoxins | 30 min | This method analyzes 6 aflatoxins. |
| E | Method for high resolution analysis of type-B trichothecenes | 12 min | This method focuses on separation out acetyldeoxynivalenol isomers. |
| F | Method for fumonisins | 15 min | Carryovers are minimized by adopting the rinsing function from the Nexera series. |
| G | Method for analysis of 10 components based on APCI | 33 min | This method based on ACPI. APCI sometimes enable better recovery rate in complex samples such as animal feed. |
Compound List for Each Method
Remarks and Precautions
LabSolutions LCMS Ver. 5.109 or later and LabSolutions Insight Ver. 3.8SP13 or later are required.
LabSolutions is a trademark of Shimadzu Corporation or its affiliated companies in Japan and/or other countries.
For Research Use Only. Not for use in diagnostic procedures.
News / Events
-
Life Science Biomarker Industry Page has been updated
Biomarkers are derived from living organisms and found in tissues, blood, and other bodily fluids. Biomarkers are indicators of biological changes in an organism and are used to diagnose disease, in prognosis, and to evaluate the efficacy and safety of pharmaceuticals. Biomarkers can be nucleic acids, proteins, peptides, lipids, and sugars, and are identified using various “omics” techniques.
-
Life Science Proteomics Industry Page has been updated
Proteomics is an academic discipline involving the comprehensive study of protein structure and function, typically by mass spectrometry and electrophoresis. Unlike the genome, the cells of an organism do not all contain the same complement of proteins, but different cells contain different proteins at different times. Proteomics uses this phenomenon to enable more efficient drug development and to determine the mechanisms of disease.
-
Cellulose nanofibers
Given that cellulose nanofibers（CNFs）offer attractive physical characteristics, such as light weight, strength, and hardness, they not only enable materials with advanced functionality, but are expected to be used as a reinforcing material that can reduce the weight of composite materials.
-
Handbook of Analysis Procedures for EPA method 533, EPA method 537.1 are now available.
The validity of the analysis performed by each laboratory needs to be confirmed by Quality Control (QC). This article section shows the general analytical procedure for fulfilling QC requirements. Note that the procedure could be modified depending on the situation in the lab and analysts.
-
Shimadzu has released the CLAM-2040, Fully Automated Sample Preparation Module for LCMS
The CLAM-2040 accompanies you on most of the analytical workflow and improves your overall throughput by drastically reducing the sample preparation time. Simply place the blood tubes in position and the CLAM-2040 performs the next steps automatically, from sample extraction, up to the LCMS analysis and data processing.
-
Per- and Polyfluoroalkyl Substances (PFAS)
Per-and polyfluoroalkyl substances (PFAS) are a group of persistent and harmful chemicals that can be commonly found in the environment globally. These anthropogenic chemicals can come from various sources such as manufacturing, industrial applications, food contact materials and consumer products, and eventually end up and accumulate in the water, soil and living organisms.
Sustainability initiatives
-
2 Zero hunger
-
6 Clean water and sanitation