LC/MS/MS Rapid Toxicology Screening System Ver.3
For LabSolutions™ LCMS
Library info for 231 compounds common in toxicology
This system improves the efficiency of simultaneous LC/MS/MS analysis methods by allowing the user to start analysis without time-consuming steps such as consideration of separation conditions and MS parameter optimization.
Rapid simultaneous analysis methods with analysis times under 15 mins are included for 231 compounds including drugs of abuse, psychoneurotic drugs and sedatives. The system also provides optimised conditions for synchronised survey scans used in screening measurements (conditions adopted for the product ion spectrum as a threshold value for the intensity in MRM).
Total solution including semi-quantitation
For each compound in the method, calibration curve information based on internal standards is available, so it is possible to obtain simple quantitative values after analysis. Using a pretreatment method based on the QuEChERS method*, it is possible to comprehensively recover compounds from biological samples. Qualitative analysis using the spectral library can be carried out during the data processing stage. In other words, the system provides a total solution encompassing pretreatment, analysis and data processing.
Pretreatment using the Micro Volume QuEChERS Kit
Example of data analysis using LabSolutions Insight Library Screening:
Using LabSolutions Insight Library Screening, you can check all of the following:
- (1) Quantitative results
- (2) Library search results
- (3) MS chromatogram
- (4) MS/MS spectra
- (5) Structural formula
List of registered compounds:
231 compounds including illegal drugs, sedatives, psychotropic drugs and medical drugs associated with many real-life cases.
Ecgonine methyl ester
Remarks and Precautions
- LabSolutions LCMS Ver. 5.109 or later and LabSolutions Insight Ver. 3.8SP1 or later are required.
- Depending on the condition and specifics of the equipment used, differences in quantitative values may occur. For accurate quantitative values, please use a calibration curve method with appropriate standard samples. In addition, scores obtained from searching in the library show the similarity of spectra and form one basis for the identification of compounds, but for more accurate compound identification it is more effective to combine multifaceted information such as retention times and sample information.
LabSolutions is a trademark of Shimadzu Corporation or its affiliated companies in Japan and/or other countries.
For Research Use Only. Not for use in diagnostic procedures.
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