SALD-2300 - Features

Laser Diffraction Particle Size Analyzer

Wide applicability

Using the SALD-MS23 sampler, the measurement range is 17nm to 2500μm for wet measurement.
For example, PSL particles with a median diameter of 50nm and stainless balls with a diameter of 2mm can be measured by a single analyzer.

The system configuration can be optimized to address various uses, purposes, measurement objects,
environments and conditions.

Various sample amounts (Suspension) can be selected according to measurement objects and purposes.

  • Sample amount for SALD-MS23 is variable: 100mL, 200mL, or 300mL.
  • Sample amount for batch cell SALD-BC23 is 12mL.
  • In the case of high-concentration sample measurement system SALD-HC23, optional indentation can be used for sample amounts ranging from 15μL to 150μL.

High sensitivity / High concentration

By enabling measurement under wide particle concentration conditions (0.1ppm to 20%), changes in particle size distribution depending on particle concentration can be evaluated.
Previously, the particle concentration of a sample had to be adjusted to meet the optimum conditions of analyzers by dilution or concentration using a centrifuge. In these cases, changes in particle size distribution, such as agglomerations or dispersions, could not be considered.

Dispersions and agglomeration can be caused by dilutions.
In some cases, dilutions can accelerate dispersions, but in other cases, they can create agglomerates. To ensure optimum, the initial particle concentration must be determined without dilutions or concentrations. After the evaluation of particle size distribution at the initial state, the effects of particle concentration from dispersions and agglomerations must be evaluated.

Wide particle concentration range must be covered to evaluate the dissolution process of sample particles.
This is necessary because the progress of dissolution makes the particle concentration low in comparison to the first particle concentration.

SALD-2300 can measure particle size distribution under the conditions of particle concentration from 0.1ppm to 20%.
When the sampler SALD-MS23 or batch cell SALD-BC23 is used, measurements are possible under conditions of concentration from 0.1ppm to 100ppm.
When the high-concentration sample measurement system SALD-HC23 is used, high-concentration samples up to 20% can be measured because the negative effects of multiple scattering are prevented.

Measurement without dilution of hand cream

In the case of hand cream, dilutions make the particle size distribution narrow. Measurements without dilutions must be done to obtain accurate measurement.

Evaluation of a fine particle included in red wine

The graph to the left shows the result of measuring red wine in the state of the undiluted solution.
The low-concentration sample can be measured as an undiluted solution.
Measuring it in this state can remove the influence of dispersion or agglomeration by the concentration operation.

Evaluation of negative electrode material of a secondary battery

At left is a graph showing the results of measuring a carbon black particle.
The agglomeration particle (micrometer range) has been dispersed to the fine particle (sub-micrometer range) by dispersion processing using a homogenizer. The sample (sample that absorbs light like the carbon black) that doesn't transmit light easily can be measured based on the improvement in sensitivity.

* Appearance and specifications are subject to change without notice.

SALD-2300 Software Now Offers Compliance with FDA 21 CFR Part 11

WingSALD II software for the SALD-2300 laser diffraction particle size analyzer now provides compliance with FDA 21 CFR Part 11.
Adopting WingSALD II software and the Shimadzu CLASS-Agent network-compatible data analysis management tool enables compliance with the security, data integrity, and audit trail requirements specified by FDA 21 CFR Part 11.


Users are managed on the basis of groups, with each user being recognized by means of a username and password. Unique groups can be created by including persons having different access privileges. Clearly defining each user's access privileges prevents unauthorized changes to settings, instrument operation, and data access.

Data Integrity

The measurement results and the accompanying measurement conditions are together automatically registered in the database. Once stored in the database, the data can no longer be deleted or overwritten, thus protecting the integrity of the data. Additionally, the stored data can be viewed in a list and searched.

Audit Trail

Records all operations performed, including logins and logouts to the system, changes in users and groups, and measurement start and completion, together with the username and the time. The recorded operational log can be registered in the database, and the history of the instrument running conditions and setting changes provides for traceability.

Software Validation

In order to verify that no alterations have been made, alteration checking software is provided with the WingSALD II software. Moreover, an analysis can be carried out using sample data supplied on the installation CD-ROM.

Supports Both Network and Stand-Alone Systems

CLASS-Agent, which supports network operations, allows centralized management on a server PC, so particle size distribution data can be combined with data from other analysis instruments and retrieved or approved in the comfort of a remote office. (In order to retrieve and approve data, Agent Manager software is needed.) Since it supports stand-alone systems, compliance with 21 CFR Part 11 can be realized with one particle size analyzer and one PC.

Network System

How Data Is Registered


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