LabSolutions Detect - Features

Overlaying chromatograms is an effective way to identify waveform differences. However, lot variations, instrument conditions, laboratory environments, and other factors may cause retention times and baselines to fluctuate. As a result, even when chromatograms are overlaid, it may not be possible to accurately detect differences. LabSolutions Detect enables overlay display after performing alignment (automatic retention time correction), allowing users to compare chromatograms without being affected by retention time shifts or baseline fluctuations. Additionally, the software can determine whether peaks fall outside the reference criteria range, making it easier to detect anomalies.

Traditionally, checking for anomalies in the quantity of controlled compounds or for the presence of unexpected impurities required a multi-step process: first identifying the target compounds and reviewing their peak information, then manually comparing unidentified peaks across multiple datasets based on retention time to determine whether they represented the same impurity. LabSolutions Detect automates this complex matching process with its clustering function, which groups similar peaks and instantly detects impurities common across datasets.

LabSolutions Detect allows users to generate anomaly analysis reports without complex settings. The report includes overlayed chromatogram displays as well as lists of compounds and impurities. It also highlights results that fall outside the predefined criteria — enabling users to review difference analysis results at a glance.

Example of a Anomaly Analysis Report

LabSolutions Detect supports data management within the LabSolutions database, allowing users to manage difference analysis reports together with the original data files — ensuring data integrity. Because it integrates seamlessly with LabSolutions, reports can be generated without the need to export or import data or method files.