PUBLICATIONS

2026

Characterization of flavor quality in sago starch produced by different processing methods: Insights from physicochemical, metabolomic, and sensory analyses

J Biosci Bioeng.

  • Giri R. Barokah 1 2
  • Azis B. Sitanggang 3
  • Eiichiro Fukusaki 1 4 5
  • Sastia P. Putri 1 4
  1. 1Department of Biotechnology, Graduate School of Engineering, Osaka University
  2. 2Research Center for Food Technology and Processing, National Research and Innovation Agency
  3. 3Department of Food Science and Technology, Faculty of Agricultural Engineering and Technology, IPB University
  4. 4Industrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University
  5. 5Osaka University Shimadzu Omics Innovation Research Laboratories, Osaka University

Prediction of the current state of beer fermentation indicators using volatile organic compounds from fermentation gas

Journal of Bioscience and Bioengineering

  • Keisuke Yamauchi 1
  • Fumika Kimura 1
  • Masahiro Furuno 1
  • Keijiro Tamaru 2
  • Kosuke Honda 2
  • Eiichiro Fukusaki 1 3 4
  1. 1Department of Biotechnology, Graduate School of Engineering, The University of Osaka
  2. 2International Center for Biotechnology, The University of Osaka
  3. 3Industrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiative, The University of Osaka
  4. 4Osaka University Shimadzu Omics Innovation Research Laboratories, The University of Osaka

Metabolomics-based investigation of compounds associated with sensory profiles of strawberries

Journal of Bioscience and Bioengineering

  • Yuri Yoshiyama 1
  • Taichiro Fujimura 2
  • Masahiro Furuno 1
  • Eiichiro Fukusaki 1 3 4
  1. 1Department of Biotechnology, Graduate School of Engineering, The University of Osaka
  2. 2Department of Food and Nutrition, Faculty of Contemporary Human Life Science, Tezukayama University
  3. 3Industrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiative, The University of Osaka
  4. 4Osaka University Shimadzu Omics Innovation Research Laboratories, The University of Osaka

GC-MS-Based Metabolite Profiling Method for Tea

Gas Chromatography-Mass Spectrometry

  • Enik Nurlaili Afifah
  • Shunsuke Miyauchi
  • Eiichiro Fukusaki
  1. Department of Biotechnology, Graduate School of Engineering, The University of Osaka, Suita, Osaka, Japan
  2. Department of Agronomy, Faculty of Agriculture, Universitas Gadjah Mada, Yogyakarta, Indonesia
  3. Department of Biotechnology, Graduate School of Engineering, The University of Osaka, Suita, Osaka, Japan
  4. Industrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiatives, Suita, Osaka, Japan
  5. The University of Osaka Shimadzu Omics Innovation Research Laboratories, International Center for Biotechnology, The University of Osaka, Suita, Osaka, Japan

Non-destructive prediction of banana ripeness using GC-MS-based volatile organic compounds profiling and orthogonal partial-least squares regression models

J Biosci Bioeng.

  • Sayaka Togami 1
  • Takumi Oishi 1
  • Masahiro Furuno 1
  • Eiichiro Fukusaki 1 2 3
  1. 1Department of Biotechnology, Graduate School of Engineering, The University of Osaka
  2. 2The University of Osaka Shimadzu Omics Innovation Research Laboratories, The University of Osaka
  3. 3Industrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiative, The University of Osaka

Spatiotemporal Dynamics of Polyphenolic Compounds in Musa spp. during Ripening Revealed by Mass Spectrometry Imaging

J Agric Food Chem.

  • Hiroko Shinoda 1
  • Shiho Ishimoto 1
  • Eiichiro Fukusaki 1 2 3
  • Shuichi Shimma 1 2 3
  1. 1Department of Biotechnology, Graduate School of Engineering, The University of Osaka.
  2. 2The University of Osaka and Shimadzu Omics Innovation Research Laboratory, The University of Osaka.
  3. 3Institute for Open and Transdisciplinary Research Initiatives, The University of Osaka.

Hydrophilic additives enhancing electrospray ionization of oligonucleotides in hexafluoro-2-propanol-free reversed-phase ion-pair liquid chromatography/mass spectrometry

Journal of Chromatography A

  • Takashi Miyazaki 1 2 3
  • Natsuyo Asano 3
  • Satoshi Yamaki 3
  • Takao Yamaguchi 1
  • Satoshi Obika 1
  1. 1Graduate School of Pharmaceutical Sciences, The University of Osaka
  2. 2Shimadzu Analytical Innovation Research Laboratories, The University of Osaka
  3. 3Shimadzu Corporation

2025

Exploration of Key Flavor Compounds in Five Grilled Salmonid Species by Integrating Volatile Profiling and Sensory Evaluation

Metabolites

  • Yuka Mori 1,2
  • Akimasa Hatanaka 2
  • Eiichiro Fukusaki 1,3
  1. 1Department of Biotechnology, Graduate School of Engineering, The University of Osaka
  2. 2Central Research Laboratory, Nissui Corporation
  3. 3Osaka University Shimadzu Omics Innovation Research Laboratories, The University of Osaka

Redefining media blending mathematically: a systematic approach for screening of medium components

Applied Microbiology and Biotechnology

  • Hirotaka Kuroda 1 2 3
  • Kazuya Sorada 1 2 3
  • Noriko Yamano-Adachi 1 4 5
  • Takeshi Omasa 1 4 5
  1. 1Graduate School of Engineering, Osaka University.
  2. 2Shimadzu Corp.
  3. 3Shimadzu Analytical Innovation Research Laboratory, Osaka University.
  4. 4Institute for Open and Transdisciplinary Research Initiatives, Osaka University.
  5. 5Manufacturing Technology Association of Biologics (MAB).

Exploration of Yeast Species Suitable for Preparation of Stable Isotope–Labeled Internal Standards Extracts (SILIS)

Mass Spectrometry

  • Taisuke Seike 1 2
  • Kahar Prihardi 3
  • Chiaki Ogino 3
  • Fumio Matsuda 1 2 4
  1. 1Department of Bioinformatics Engineering, Graduate School of Information Science and Technology, The University of Osaka
  2. 2Industrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiatives, The University of Osaka
  3. 3Department of Chemical Engineering, Graduate School of Engineering, Kobe University
  4. 4Osaka University Shimadzu Analytical Innovation Research Laboratory, Graduate School of Engineering, The University of Osaka

Comprehensive GC/MS Profiling of Volatile Organic Compounds in Whole and Glandular Saliva Using MonoTrap Micro-Extraction

Metabolites

  • Asuka Mori 1
  • Masae Kuboniwa 2
  • Eiichiro Fukusaki 1 3
  1. 1Department of Biotechnology, Graduate School of Engineering, The University of Osaka
  2. 2Department of Preventive Dentistry, Graduate School of Dentistry, The University of Osaka
  3. 3Osaka University Shimadzu Omics Innovation Research Laboratories, The University of Osaka

Exploration of yeast species suitable for preparation of stable isotope-labeled internal standards extracts (SILIS)

Mass Spectrometry

  • Taisuke Seike 1 2
  • Kahar Prihardi 3
  • Chiaki Ogino 3
  • Fumio Matsuda 1 2 4
  1. 1Department of Bioinformatics Engineering, Graduate School of Information Science and Technology, Osaka University
  2. 2Industrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University
  3. 3Department of Chemical Engineering, Graduate School of Engineering, Kobe University
  4. 4Osaka University Shimadzu Analytical Innovation Research Laboratory, Graduate School of Engineering, Osaka University

Metabolites and nutritional variations of phenotypic diversity in Kopyor coconut (Cocos nucifera L. var. Kopyor)

J Biosci Bioeng.

  • Mercy Bientri Yunindanova 1 2
  • Hengky Novarianto 3
  • Eiichiro Fukusaki 1 4 5
  • Sastia Prama Putri 1 4
  1. 1Department of Biotechnology, Graduate School of Engineering, Osaka University
  2. 2Study Program of Agrotechnology, Faculty of Agriculture, Universitas Sebelas Maret
  3. 3National Research and Innovation Agency (BRIN)
  4. 4Industrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiatives
  5. 5Osaka University Shimadzu Omics Innovation Research Laboratories, International Center for Biotechnology, Osaka University

Metabolite and Sensory Profiling of Microwave-Assisted and Ultrasonic-Assisted Alkalized Cocoa Powders

J Food Sci.

  • Mary Faith Adan 1
  • Dimas Rahadian Aji Muhammad 2 3
  • Danar Praseptiangga 2 3
  • Eiichiro Fukusaki 1 4 5
  • Sastia Prama Putri 1
  1. 1Department of Biotechnology, Graduate School of Engineering, Osaka University
  2. 2Department of Food Science and Technology, Faculty of Agriculture, Universitas Sebelas Maret
  3. 3Research Collaboration Center for Traditional Fermentation, Universitas Sebelas Maret
  4. 4Industrial Biotechnology Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University
  5. 5Osaka University-Shimadzu Omics Innovation Research Laboratories, Osaka University

Microbial Intervention in the Soaking Step during Tempeh Preparation to Modulate B Vitamin Contents: A Metabolomics Approach

Prev Nutr Food Sci.

  • Rifqi Ahmad Riyanto 1 2
  • Eiichiro Fukusaki 1 3 4
  • Sastia Prama Putri 1 3
  1. 1Department of Biotechnology, Graduate School of Engineering, The University of Osaka
  2. 2Department of Food Technology, Faculty of Agriculture, Universitas Sultan Ageng Tirtayasa
  3. 3Industrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiatives, The University of Osaka
  4. 4Osaka University Shimadzu Omics Innovation Research Laboratories, The University of Osaka

Metabolomics-based investigation of the differences between traditional and modern soy sauce

J Biosci Bioeng.

  • Yoshika Maekawa 1
  • Miki Nakamura 2
  • Miho Imamura 2
  • Eiichiro Fukusaki 1 3 4
  1. 1Department of Biotechnology, Graduate School of Engineering, Osaka University
  2. 2Research and Development Division, Kikkoman Corporation
  3. 3Industrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiative, Osaka University
  4. 4Osaka University Shimadzu Omics Innovation Research Laboratories, Osaka University

Metabolic Engineering of the 5-Aminolevulinate Biosynthetic Pathway in E. coli Improves Efficiency of Hemoprotein-Based Biocatalysis

Angew Chem Int Ed Engl.

  • Shunsuke Kato 1
  • Miteki Abe 1
  • Nobuyuki Okahashi 2 3 4
  • Shinya Ariyasu >5
  • Fumio Matsuda 2 3 4
  • Osami Shoji >5
  • Takashi Hayashi 1
  1. 1Department of Applied Chemistry, Graduate School of Engineering, The University of Osaka
  2. 2Department of Bioinformatic Engineering, Graduate School of Information Science and Technology, The University of Osaka
  3. 3Department of Biotechnology, The University of Osaka and Shimadzu Analytical Innovation Laboratories, Graduate School of Engineering, The University of Osaka
  4. 4Industrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiatives, The University of Osaka
  5. 5Department of Chemistry, Graduate School of Science, Nagoya University

Metabolomics reveals the impact of different de-pulping methods on flavor modulation and their potential quality markers in Indonesian cocoa beans

Food Bioscience

  • Aulia Gusning Ati a
  • Indah Anita Sari b
  • Hendy Firmanto b
  • Abdul Malik b
  • Eiichiro Fukusaki a c d
  • Sastia Prama Putri a c
  1. aDepartment of Biotechnology, Graduate School of Engineering, Osaka University
  2. bIndonesian Coffee and Cocoa Research Institute
  3. cIndustrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiatives
  4. dOsaka University Shimadzu Omics Innovation Research Laboratories, Osaka University

ATP Supply from Cytosol to Mitochondria Is an Additional Role of Aerobic Glycolysis to Prevent Programmed Cell Death by Maintenance of Mitochondrial Membrane Potential

Metabolites.

  • Akane Sawai 1
  • Takeo Taniguchi 1
  • Kohsuke Noguchi 1
  • Taisuke Seike 1
  • Nobuyuki Okahashi 1 2
  • Masak Takaine 3 4
  • Fumio Matsuda 1 2
  1. 1Department of Bioinformatic Engineering, Graduate School of Information Science and Technology, The University of Osaka
  2. 2Shimadzu Analytical Innovation Research Laboratory, Graduate School of Engineering, The University of Osaka
  3. 3Gunma University Initiative for Advanced Research (GIAR), Gunma University
  4. 4Institute for Molecular and Cellular Regulation (IMCR), Gunma University

電荷検出質量分析による遺伝子治療用ウイルスベクターの特性評価

J. Mass Spectrom. Soc. Jpn.

  • 中塚遼治 1, 2, 3
  1. 1大阪大学大学院工学研究科
  2. 2大阪大学・島津分析イノベーション協働研究所
  3. 3株式会社島津製作所

Correlation between sensory attributes and Metabolomic profiles of cocoa liquor from different cacao genotypes

Food Chem X.

  • Enik Nurlaili Afifah 1 2
  • Indah Anita Sari 3
  • Agung Wahyu Susilo 3
  • Hendy Firmanto 3
  • Abdul Malik 3
  • Eiichiro Fukusaki 1 4 5
  • Sastia Prama Putri 1 4
  1. 1Department of Biotechnology, Graduate School of Engineering, Osaka University
  2. 2Department of Agronomy, Faculty of Agriculture, Universitas Gadjah Mada
  3. 3Indonesian Coffee and Cocoa Research Institute
  4. 4Industrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiatives
  5. 5Osaka University Shimadzu Omics Innovation Research Laboratories, International Center for Biotechnology, Osaka University

Comparative metabolome analysis of sake yeast with enhanced fermentation performance in sake fermentation conditions

J Biosci Bioeng.

  • Kotaro Mori 1 2
  • Taisuke Seike 1 3
  • Nobuyuki Okahashi 1 3 4
  • Toshinari Takahashi 2
  • Fumio Matsuda 1 3 4
  1. 1Department of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University
  2. 2General Research Laboratory, Kiku-Masamune Sake Brewing Co. Ltd.
  3. 3Industrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University
  4. 4Osaka University Shimadzu Analytical Innovation Research Laboratory, Graduate School of Engineering, Osaka University

Data-independent acquisition-based lipidomics reveals lipidome alterations associated with growth of Saccharomyces cerevisiae at low temperature

Journal of Bioscience and Bioengineering

  • Daiki Hara 1
  • Nobuyuki Okahashi 1 2 3
  • Taisuke Seike 1 2
  • Junko Iida 3 4
  • Fumio Matsuda 1 2 3
  1. 1Department of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University
  2. 2Industrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University
  3. 3Osaka University Shimadzu Analytical Innovation Research Laboratory, Graduate School of Engineering, Osaka University
  4. 4Analytical and Measuring Instruments Division, Shimadzu Corporation

13C-metabolic flux analysis of Saccharomyces cerevisiae in complex media

Metab Eng Commun.

  • Hayato Fujiwara 1
  • Nobuyuki Okahashi 1 2 3
  • Taisuke Seike 1
  • Fumio Matsuda 1 2 3
  1. 1Department of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University
  2. 2Osaka University Shimadzu Omics Innovation Research Laboratories, Osaka University
  3. 3Industrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University

Metabolic profiling reveals distinctive ripening dynamics in ethylene-treated Musa balbisiana cv. ‘Pisang Klutuk Wulung’ compared to commercial Cavendish banana

Journal of Bioscience and Bioengineering

  • Cindy Novianti 1 2
  • Lutfi Dewi Nirmala Sari 2
  • Husna Nugrahapraja 2 3 5
  • Sony Suhandono 2 4
  • Fenny Martha Dwivany 2 3 4 5
  • Sastia Prama Putri 2 6 7
  • Eiichiro Fukusaki 6 7 8
  1. 1Doctoral Program of Biology, School of Life Sciences and Technology, Institut Teknologi Bandung
  2. 2School of Life Sciences and Technology, Institut Teknologi Bandung
  3. 3Biosciences and Biotechnology Research Center, Institut Teknologi Bandung
  4. 4Nanoscience and Nanotechnology Research Center, Institut Teknologi Bandung
  5. 5Bali International Research Center for Banana, Gedung Widyasaba, Universitas Udayana
  6. 6Department of Biotechnology, Graduate School of Engineering, Osaka University
  7. 7Industrial Biotechnology Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University
  8. 8Osaka University-Shimadzu Analytical Innovation Research Laboratories, Osaka University

Gas chromatography-mass spectrometry metabolic profiling and sensory evaluation of greenhouse mangoes (Mangifera indica L. 'Irwin') over multiple harvest seasons

J Biosci Bioeng.

  • Miwa Sato 1 2
  • Eiichiro Fukusaki 1 3 4
  1. 1Department of Biotechnology, Graduate School of Engineering, Osaka University
  2. 2Miyazaki Agricultural Research Institute
  3. 3Osaka University Shimadzu Analytical Innovation Research Laboratory, Osaka University
  4. 4Institute for Open and Transdisciplinary Research Initiatives, Osaka University

ΔΔ G Method for Elucidating Key Control Reactions from Relative Quantification Metabolome Data: Comparative Analysis of Yeast Glycolysis

Anal Chem.

  • Fumio Matsuda 1 2
  • Ayumu Kamiyama 1
  • Kazuki Yamasaki 1
  • Taisuke Seike 1
  • Nobuyuki Okahashi 1 2
  1. 1Graduate School of Information Science and Technology, Osaka University
  2. 2Osaka University Shimadzu Omics Innovation Research Laboratories, Osaka University

Separation of deaminated impurities from the desired oligonucleotides using supercritical fluid chromatography

Journal of Chromatography A

  • 〇Momoka Hayashida1,2,3
  • Risa Suzuki 3
  • Shinnosuke Horie 2,3,4
  • Junichi Masuda 3
  • Takao Yamaguchi 1
  • Satoshi Obika 1
  1. 1Graduate School of Pharmaceutical Sciences, Osaka University
  2. 2Osaka University Shimadzu Analytical Innovation Research Laboratories
  3. 3Shimadzu Corporation
  4. 4Shimadzu Europa GmbH

Biological age prediction using a DNN model based on pathways of steroidogenesis

Science Advances

  • Qiuyi Wang†‡
  • Zi Wang†
  • Kenji Mizuguchi
  • Toshifumi Takao
  1. Institute for Protein Research, Osaka University
  2. †these authors contributed equally to this work.
  3. ‡Shimadzu corporation.

Application of silica monoliths for improved storage stability of metabolites in human plasma

Journal of Bioscience and Bioengineering

  • Kazuhiro Kawamura 1 2 3
  • Eiichiro Fukusaki 1 3 4
  1. 1Department of Biotechnology, Graduate School of Engineering, Osaka University
  2. 2Life Science Business Department, Shimadzu Corporation
  3. 3Osaka University Shimadzu Analytical Innovation Research Laboratory, Osaka University
  4. 4Institute for Open and Transdisciplinary Research Initiatives

Closed genome sequence of Fretibacterium fastidiosum, a potential contributor to periodontal disease

Microbiol Resour Announc.

  • Asuka Mori 1
  • Mashu Kudoh 2
  • Masae Kuboniwa 2
  • Christian Rückert-Reed 3 4
  • Tobias Busche 3 4
  • Marion Eisenhut 3 5
  • Eiichiro Fukusaki 1 6 7
  • Andrea Bräutigam 3 5
  • Bianca Laker 3 5
  1. 1Department of Biotechnology, Graduate School of Engineering, Osaka University
  2. 2Department of Preventive Dentistry, Graduate School of Dentistry, Osaka University
  3. 3Center for Biotechnology (CeBiTec), Bielefeld University
  4. 4Medical School OWL, Bielefeld University, Bielefeld, North Rhine-Westphalia, Germany
  5. 5Comp utational Biology, Faculty of Biology, Bielefeld University
  6. 6Osaka University Shimadzu Omics Innovation Research Laboratories, Osaka University
  7. 7Industrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiative, Osaka University

Effect of pre-drying on flavor modulation in Indonesian cocoa beans: A metabolomics study of key flavor compounds and sensory profiles

Food Bioscience

  • Aulia Gusning Ati a
  • Indah Anita Sari b
  • Hendy Firmanto b
  • Abdul Malik b
  • Eiichiro Fukusaki a c d
  • Sastia Prama Putri a c
  1. aDepartment of Biotechnology, Graduate School of Engineering, Osaka University
  2. bIndonesian Coffee and Cocoa Research Institute
  3. cIndustrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiatives
  4. dOsaka University Shimadzu Analytical Innovation Research Laboratories, Osaka University

Combinatorial Nonribosomal Peptide Synthetase Libraries Using the SEAM-Combi-OGAB Method

ACS Synth Biol.

  • Varada Jagadeesh 1
  • Nobuyuki Okahashi 2 3
  • Fumio Matsuda 2 3
  • Kenji Tsuge 1
  • Akihiko Kondo 1
  1. 1Graduate School of Science, Technology, and Innovation, Kobe University.
  2. 2Department of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University.
  3. 3Department of Biotechnology, Osaka University Shimadzu Analytical Innovation Research Laboratory, Graduate School of Engineering, Osaka University.

Enhancing constituent estimation in nucleic acid mixture models using spectral annealing inference and MS/MS information

Frontiers in Analytical Science

  • Taichi Tomono1,2,3*
  • Satoshi HaraSatoshi Hara4
  • Junko Iida2,5
  • Takashi Washio1,6
  1. 1The Institute of Scientific and Industrial Research, Osaka University
  2. 2Shimadzu Analytical Innovation Research Laboratories, Osaka University
  3. 3AI Solution Unit, Technology Research Laboratory, Shimadzu Corporation
  4. 4Graduate School of Informatics and Engineering, The University of Electro-Communication
  5. 5Life Science Business Department, Analytical and Measuring Instruments Division, Shimadzu Corporation
  6. 6Faculty of Business and Commerce, Kansai University

Conserved metabolic adaptation mechanisms in cancer cells and yeast against mitochondrial dysfunction indicate an additional role of aerobic glycolysis for cell survival

bioRxiv

  • Akane Sawai 1
  • Takeo Taniguchi 1
  • Kohsuke Noguchi 1
  • Taisuke Seike 1
  • Nobuyuki Okahashi 1 2
  • Masak Takaine 3 4
  • Fumio Matsuda 1 2
  1. 1Department of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University
  2. 2Osaka University Shimadzu Analytical Innovation Research Laboratory, Graduate School of Engineering, Osaka University
  3. 3Gunma University Initiative for Advanced Research (GIAR), Gunma University
  4. 4Institute for Molecular and Cellular Regulation (IMCR), Gunma University

Metabolic profiling reveals distinctive ripening dynamics in ethylene-treated Musa balbisiana cv. 'Pisang Klutuk Wulung' compared to commercial Cavendish banana

J Biosci Bioeng

  • Cindy Novianti 1 2
  • Lutfi Dewi Nirmala Sari 2
  • Husna Nugrahapraja 2 3 5
  • Sony Suhandono 2 4
  • Fenny Martha Dwivany 2 3 4 5
  • Sastia Prama Putri 2 6 7
  • Eiichiro Fukusaki 6 7 8
  1. 1Doctoral Program of Biology, School of Life Sciences and Technology, Institut Teknologi Bandung
  2. 2School of Life Sciences and Technology, Institut Teknologi Bandung
  3. 3Biosciences and Biotechnology Research Center, Institut Teknologi Bandung
  4. 4Nanoscience and Nanotechnology Research Center, Institut Teknologi Bandung
  5. 5Bali International Research Center for Banana, Gedung Widyasaba, Universitas Udayana
  6. 6Department of Biotechnology, Graduate School of Engineering, Osaka University
  7. 7Industrial Biotechnology Division, Institute for Open and Transdisciplinary Research Initiatives
  8. 8Osaka University-Shimadzu Omics Innovation Research Laboratories, Osaka University

Gas chromatography–mass spectrometry metabolic profiling and sensory evaluation of greenhouse mangoes (Mangifera indica L. ‘Irwin’) over multiple harvest seasons

Journal of Bioscience and Bioengineering

  • Miwa Sato 1 2
  • Eiichiro Fukusaki 1 3 4
  1. 1Department of Biotechnology, Graduate School of Engineering, Osaka University
  2. 2Miyazaki Agricultural Research Institute
  3. 3Osaka University Shimadzu Analytical Innovation Research Laboratory, Osaka University
  4. 4Institute for Open and Transdisciplinary Research Initiatives, Osaka University

2024

Characterization of fine-flavor cocoa in parent-hybrid combinations using metabolomics approach

Food Chem X. Volume 24, 30 December 2024, 101832

  • Enik Nurlaili Afifah 1 2
  • Indah Anita Sari 3
  • Agung Wahyu Susilo 3
  • Abdul Malik 3
  • Eiichiro Fukusaki 1 4 5
  • Sastia Prama Putri 1 4
  1. 1Department of Biotechnology, Graduate School of Engineering, Osaka University
  2. 2Department of Agronomy, Faculty of Agriculture, Universitas Gadjah Mada
  3. 3Indonesian Coffee and Cocoa Research Institute
  4. 4Industrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiatives
  5. 5Osaka University Shimadzu Omics Innovation Research Laboratories, International Center for Biotechnology, Osaka University

Imaging Lipidomics and Metallomics of Brown Rice Cultivars Used for Sake Production

Mass Spectrom (Tokyo). 2024;13(1):A0164

  • Eliza Farestiani 1
  • Yoshihiro Tamada 1 2
  • Koji Okuda 3
  • Eiichiro Fukusaki 1 4 5
  • Shuichi Shimma 1 4 5
  1. 1Department of Biotechnology, Graduate School of Engineering, Osaka University
  2. 2Hakutsuru Sake Brewing Co., Ltd.
  3. 3Solutions COE, Analytical and Measuring Instruments Division, Shimadzu Corporation
  4. 4nstitute for Open and Transdisciplinary Research Initiatives, Osaka University
  5. 5Osaka University Shimadzu Omics Innovation Research Laboratory, Osaka University

Combination of Probe Electrospray Ionization Mass Spectrometry and Mass Spectrometry Imaging to Analyze Plant Alkaloids in Narcissus tazetta

Mass Spectrom (Tokyo). 2024;13(1):A0163

  • Kaoru Nakagawa 1
  • Tetsuo Iida 1
  • Manami Kobayashi 1
  • Shuichi Shimma 2 3
  1. 1Solutions COE, Analytical & Measuring Instruments Division, Shimadzu Corporation.
  2. 2Department of Biotechnology, Graduate School of Engineering, Osaka University.
  3. 3Institute for Open and Transdisciplinary Research Initiatives, Osaka University.

Effect of sodium metabisulfite treatment and storage condition on metabolic profile of young coconut (Cocos nucifera L.)

J Biosci Bioeng. 2024 Dec;138(6):515-521.

  • Della Rahmawati 1 2
  • Mary Faith Yamballa Adan 1
  • Muhammad Maulana Malikul Ikram 1
  • Marvin Nathanael Iman 1
  • Eiichiro Fukusaki 1 3 4
  • Sastia Prama Putri 1 3
  1. 1Department of Biotechnology, Graduate School of Engineering, Osaka University
  2. 2Department of Food Technology, Faculty of Life Science and Technology, Swiss German University
  3. 3Industrial Biotechnology Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University
  4. 4Osaka University-Shimadzu Omics Innovation Research Laboratories, Osaka University

Data Processing of Product Ion Spectra: Methods to Control False Discovery Rate in Compound Search Results for Untargeted Metabolomics

Mass Spectrom (Tokyo). 2024;13(1):A0155

  • Fumio Matsuda 1 2
  1. 1Graduate School of Information Science and Technology, Osaka University.
  2. 2Osaka University Shimadzu Omics Innovation Research Laboratories, Osaka University.

Novel mimetic tissue standards for precise quantitative mass spectrometry imaging of drug and neurotransmitter concentrations in rat brain tissues

Anal Bioanal Chem. 2024 Nov;416(26):5579-5593.

  • Kenichi Watanabe 1
  • Sayo Takayama 1
  • Toichiro Yamada 1
  • Masayo Hashimoto 1
  • Jun Tadano 2
  • Tetsuya Nakagawa 2
  • Takao Watanabe 3
  • Eiichiro Fukusaki 4 5 6
  • Izuru Miyawaki 1
  • Shuichi Shimma 4 5 6
  1. 1Preclinical Research Unit, Sumitomo Pharma Co., Ltd.
  2. 2Research Planning & Coordination, Sumitomo Pharma Co.
  3. 3Drug Research Division, Sumitomo Pharma Co.
  4. 4Department of Biotechnology, Graduate School of Engineering, Osaka University.
  5. 5Institute for Open and Transdisciplinary Research Initiatives, Osaka University.
  6. 6Osaka University Shimadzu Omics Innovation Research Laboratory, Osaka University.

Novel sampling and gas-phase derivatization strategy: Proof-of-concept by profiling ionic polar metabolites using gas chromatography-mass spectrometry

J Biosci Bioeng. 2024 Nov;138(5):462-468

  • Kazuhiro Kawamura 1 2 3
  • Eiichiro Fukusaki 1 3 4
  1. 1Department of Biotechnology, Graduate School of Engineering, Osaka University
  2. 2Life Science Business Department, Shimadzu Corporation
  3. 3Osaka University Shimadzu Analytical Innovation Research Laboratory, Osaka University
  4. 4Institute for Open and Transdisciplinary Research Initiatives

Mass spectrometry imaging of gamma-aminobutyric acid and glutamic acid decarboxylase reactions at various stages of banana ripening

J Biosci Bioeng. 2024 Oct 30:S1389-1723(24)00283-4.

  • Shiho Ishimoto 1
  • Eiichiro Fukusaki 1 2 3
  • Shuichi Shimma 1 2 3
  1. 1Department of Biotechnology, Graduate School of Engineering, Osaka University
  2. 2Osaka University Shimadzu Omics Innovation Research Laboratory, Osaka University
  3. 3Institute for Open and Transdisciplinary Research Initiatives, Osaka University

Multimass Analysis of Adeno-Associated Virus Vectors by Orbitrap-Based Charge Detection Mass Spectrometry

Analytical Chemistry 2024 96 (42), 17037-17046

  • Ryoji Nakatsuka1, 2, 3
  • Yuki Yamaguchi1
  • Kiichi Hirohata1
  • Saki Shimojo1
  • Makoto Murakami1
  • Mark Allen Vergara Rocafort1
  • Yasuo Tsunaka1
  • Mitsuko Fukuhara1, 4
  • Tetsuo Torisu1
  • Susumu Uchiyama1
  1. 1Department of Biotechnology, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan
  2. 2Technology Research Laboratory, Shimadzu Corporation, 1 Nishinokyo-Kuwabaracho, Nakagyo-ku, Kyoto 604-8511, Japan
  3. 3Osaka University Shimadzu Analytical Innovation Research Laboratories, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan
  4. 4U-Medico Inc., 2-1 Yamadaoka, Suita, Osaka 565-0871

Towards more realistic cultivated meat by rethinking bioengineering approaches

Trends in Biotechnology

  • Marie Piantino1
  • Quentin Muller1
  • Chika Nakadozono1,2,3,4
  • Asuka Yamada1,2,5
  • Michiya Matsusaki1,2
  1. 1Consortium for Future Innovation by Cultured Meat, Osaka, Japan
  2. 2Department of Applied Chemistry, Graduate School of Engineering, Osaka University, Osaka, Japan
  3. 3Shimadzu Analytical Innovation Research Laboratories, Osaka University, Osaka, Japan
  4. 4Shimadzu Corporation, Kyoto, Japan
  5. 5Toppan Holdings Inc., Business Development Division, Technical Research Institute, Saitama, Japan

Novel mimetic tissue standards for precise quantitative mass spectrometry imaging of drug and neurotransmitter concentrations in rat brain tissues

Anal Bioanal Chem

  • Kenichi Watanabe 1
  • Sayo Takayama 1
  • Toichiro Yamada 1
  • Masayo Hashimoto 1
  • Jun Tadano 2
  • Tetsuya Nakagawa 2
  • Takao Watanabe 3
  • Eiichiro Fukusaki 4 5 6
  • Izuru Miyawaki 1
  • Shuichi Shimma 4 5 6
  1. 1Preclinical Research Unit, Sumitomo Pharma Co., Ltd
  2. 2Research Planning & Coordination, Sumitomo Pharma Co., Ltd
  3. 3Drug Research Division, Sumitomo Pharma Co., Ltd
  4. 4Department of Biotechnology, Graduate School of Engineering, Osaka University
  5. 5Institute for Open and Transdisciplinary Research Initiatives, Osaka University
  6. 6Osaka University Shimadzu Omics Innovation Research Laboratory, Osaka University.

New insights into the characteristic flavor components of traditional sour beers such as Lambic and Flanders Red Ale beers

J Biosci Bioeng. 2024 Jul;138(1):54-62

  • Kyoya Onishi 1
  • Masahiro Furuno 1
  • Asuka Mori 1
  • Eiichiro Fukusaki 1 2 3
  1. 1Department of Biotechnology, Graduate School of Engineering, Osaka University
  2. 2Industrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiative, Osaka University
  3. 3Osaka University Shimadzu Omics Innovation Research Laboratories, Osaka University

Characteristics of kopyor coconut (Cocos nucifera L.) using sensory analysis and metabolomics-based approach

Biosci Bioeng. 2024 Jul;138(1):44-53

  • Mercy Bientri Yunindanova 1 2
  • Sastia Prama Putri 1 3
  • Hengky Novarianto 5
  • Eiichiro Fukusaki 1 3 4
  1. 1Department of Biotechnology, Graduate School of Engineering, Osaka University
  2. 2Study Program of Agrotechnology, Faculty of Agriculture, Universitas Sebelas Maret
  3. 3Industrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiatives
  4. 4Osaka University Shimadzu Omics Innovation Research Laboratories, International Center for Biotechnology
  5. 5National Research and Innovation Agency (BRIN)

Multidisciplinary approach combining food metabolomics and epidemiology identifies meglutol as an important bioactive metabolite in tempe, an Indonesian fermented food

Food Chem. 2024 Jul 15:446:138744

  • Marvin N. Iman a 1
  • Danielle E. Haslam b d 1
  • Liming Liang e f
  • Kai Guo g
  • Kaumudi Joshipura e g
  • Cynthia M. Pérez h
  • Clary Clish i
  • Katherine L. Tucker j
  • JoAnn E. Manson c
  • Shilpa N. Bhupathiraju b d 2
  • Eiichiro Fukusaki a k l 2
  • Jessica Lasky-Su b 2
  • Sastia P. Putri a l
  1. aDepartment of Biotechnology, Graduate School of Engineering,
  2. bChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School
  3. cDivision of Preventive Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School
  4. dDepartment of Nutrition, Harvard T.H. Chan School of Public Health,
  5. eDepartment of Epidemiology, Harvard T.H. Chan School of Public Health
  6. fDepartment of Biostatistics, Harvard T.H. Chan School of Public Health
  7. gCenter for Clinical Research and Health Promotion, Graduate School of Public Health, University of Puerto Rico Medical Sciences Campus
  8. hDepartment of Biostatistics and Epidemiology, Graduate School of Public Health, University of Puerto Rico Medical Sciences Campus
  9. iBroad Institute of Massachusetts Institute of Technology and Harvard,
  10. jDepartment of Biomedical and Nutritional Sciences, University of Massachusetts Lowell
  11. kIndustrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University
  12. lOsaka University-Shimadzu Omics Innovation Research Laboratories, Osaka University

Metabolomic characterization of monoclonal antibody-producing Chinese hamster lung (CHL)-YN cells in glucose-controlled serum-free fed-batch operation

Biotechnology and Bioengineering

  • Puriwat Sukwattananipaat1
  • Hirotaka Kuroda1, 2, 3
  • Noriko Yamano-Adachi1, 4, 5
  • Takeshi Omasa1, 4, 5
  1. 1Graduate School of Engineering, Osaka University
  2. 2Shimadzu Corp., 1 Nishinokyo Kuwabaracho
  3. 3Shimadzu Analytical Innovation Research Laboratories
  4. 4Institute for Open and Transdisciplinary Research Initiatives, Osaka University
  5. 5Manufacturing Technology Association of Biologics (MAB)

13C-metabolic flux analysis reveals metabolic rewiring in HL-60 neutrophil-like cells through differentiation and immune stimulation

Metab Eng Commun. 2024 May 27:18:e00239

  • Takeo Taniguchi 1
  • Nobuyuki Okahashi 1 2 3
  • Fumio Matsuda 1 2 3
  1. 1Department of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University
  2. 2Department of Biotechnology, Osaka University Shimadzu Analytical Innovation Research Laboratory, Graduate School of Engineering, Osaka University
  3. 3Industrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University

New insights into the characteristic flavor components of traditional sour beers such as Lambic and Flanders Red Ale beers

J Biosci Bioeng. 2024 Apr 22:S1389-1723(24)00111-7

  • Kyoya Onishi 1
  • Masahiro Furuno 1
  • Asuka Mori 1
  • Eiichiro Fukusaki 1 2 3
  1. 1Department of Biotechnology, Graduate School of Engineering, Osaka University
  2. 2Industrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiative, Osaka University
  3. 3Osaka University Shimadzu Omics Innovation Research Laboratories, Osaka University

Identification and enzymatic properties of arginine decarboxylase from Aspergillus oryzae

Appl Environ Microbiol. 2024 Apr 16:e0029424

  • Yui Murakami 1
  • Soichiro Ikuta 2
  • Wakao Fukuda 2
  • Naoki Akasaka 1 3
  • Jun-Ichi Maruyama 4 5
  • Shuichi Shinma 6 7 8
  • Eiichiro Fukusaki 6 7 8
  • Shinsuke Fujiwara 1 2
  1. 1Department of Biosciences, Graduate School of Science and Technology, Kwansei-Gakuin University
  2. 2Department of Biosciences, School of Biological and Environmental Sciences
  3. 3Laboratory for Circular Bioeconomy Development, Office of Society-Academia Collaboration for Innovation, Kyoto University
  4. 4Department of Biotechnology, The University of Tokyo
  5. 5Collaborative Research Institute for Innovative Microbiology, The University of Tokyo
  6. 6Department of Biotechnology, Graduate School of Engineering, Osaka University
  7. 7Osaka University Shimadzu Analytical Innovation Laboratory, Osaka University
  8. 8Institute for Open and Transdisciplinary Research Initiatives (OTRI), Osaka University

Development of a Mass Spectrometry Imaging Method to Evaluate the Penetration of Moisturizing Components Coated on Surgical Gloves into Artificial Membranes

Mass Spectrom (Tokyo). 2024;13(1):A0145

  • Erika Nagano 1
  • Kazuki Odake 1
  • Toru Akiyoshi 2
  • Shuichi Shimma 1 3 4 5
  1. 1Research and Development Department, Miruion Corporation
  2. 2Marketing Department, Cardinal Health K.K.
  3. 3Department of Biotechnology, Graduate School of Engineering, Osaka University
  4. 4Institute for Open and Transdisciplinary Research Initiatives, Osaka University
  5. 5Osaka University Shimadzu Omics Innovation Research Laboratory, Osaka University

Metabolome analysis of metabolic burden in Escherichia coli caused by overexpression of green fluorescent protein and delta-rhodopsin

J Biosci Bioeng. 2024 Mar;137(3):187-194.

  • Chinatsu Matsuyama 1
  • Taisuke Seike 1
  • Nobuyuki Okahashi 1,2
  • Teppei Niide 1
  • Kiyotaka Y. Hara 3
  • Yoko Hirono-Hara 4
  • Jun Ishii 5
  • Hiroshi Shimizu 1
  • Yoshihiro Toya 1
  • Fumio Matsuda 1,2
  1. 1Graduate School of Information Science and Technology, Osaka University
  2. 2Osaka University Shimadzu Omics Innovation Research Laboratories, Osaka University
  3. 3Department of Environmental and Life Sciences, School of Food and Nutritional Sciences, University of Shizuoka
  4. 4396Bio Inc.
  5. 5Engineering Biology Research Center, Kobe University

Rice grain structural characteristics of sake rice cultivar Hakutsurunishiki for daiginjo-shu brewing

Biosci Biotechnol Biochem. 2024 Mar 22;88(4):445-452

  • Yoshihiro Tamada 1, 2
  • Takuya Asai 1
  • Takafumi Kubodera 1
  • Takahiro Akashi 1
  • Eiichiro Fukusaki 2, 3, 4
  • Shuichi Shimma 2, 3, 4
  1. 1Hakutsuru Sake Brewing Co., Ltd.
  2. 2Department of Biotechnology, Graduate School of Engineering, Osaka University
  3. 3Osaka University Shimadzu Omics Innovation Research Laboratory, Osaka University
  4. 4Institute for Open and Transdisciplinary Research Initiatives, Osaka University

Multidisciplinary approach combining food metabolomics and epidemiology identifies meglutol as an important bioactive metabolite in tempe, an Indonesian fermented food

Food Chem. 2024 Feb 16:446:138744.

  • Marvin N. Iman a,1
  • Danielle E. Haslam b, d, 1
  • Liming Liang e, f
  • Kai Guo g
  • Kaumudi Joshipura e, g
  • Cynthia M. Pérez h
  • Clary Clish i
  • Katherine L. Tucker j
  • JoAnn E. Manson c
  • Shilpa N. Bhupathiraju b d 2
  • Eiichiro Fukusaki a k l 2
  • Jessica Lasky-Su b 2
  • Sastia P. Putri a l 2
  1. aDepartment of Biotechnology, Graduate School of Engineering, Osaka University
  2. bChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School
  3. cDivision of Preventive Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School
  4. dDepartment of Nutrition, Harvard T.H. Chan School of Public Health
  5. eDepartment of Epidemiology, Harvard T.H. Chan School of Public Health
  6. fDepartment of Biostatistics, Harvard T.H. Chan School of Public Health
  7. gCenter for Clinical Research and Health Promotion, Graduate School of Public Health, University of Puerto Rico Medical Sciences Campus
  8. hDepartment of Biostatistics and Epidemiology, Graduate School of Public Health, University of Puerto Rico Medical Sciences Campus
  9. iBroad Institute of Massachusetts Institute of Technology and Harvard
  10. jDepartment of Biomedical and Nutritional Sciences, University of Massachusetts Lowell
  11. kIndustrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University
  12. lOsaka University-Shimadzu Omics Innovation Research Laboratories, Osaka University
  13. 1These authors contributed equally: Marvin N. Iman, Danielle E. Haslam.
  14. 2Joint senior authors, contributed equally: Shilpa N. Bhupathiraju, Eiichiro Fukusaki, Jessica Lasky-Su, Sastia P. Putri.

A Bayesian approach for constituent estimation in nucleic acid mixture models

Front. Anal. Sci., 08 Jan 2024, 10.3389/frans.2023.1301602

  • Taichi Tomono1,2,3
  • Satoshi Hara1
  • Yusuke Nakai2
  • Kazuma Takahara2
  • Junko Iida3,4
  • Takashi Washio1
  1. 1Department of Reasoning for Intelligence, The Institute of Scientific and Industrial Research, Osaka University
  2. 2AI Solution Unit, Technology Research Laboratory, Shimadzu Corporation
  3. 3Shimadzu Analytical Innovation Research Laboratories, Osaka University
  4. 4Life Science Business Department, Analytical and Measuring Instruments Division, Shimadzu Corporation

2023

Data Processing of Product Ion Spectra: Redundancy of Product Ion Spectra of Small Molecules in Data-Dependent Acquisition Dataset

Mass Spectrom (Tokyo). 2023;12(1):A0138.

  • Fumio Matsuda
  1. Department of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University
  2. Osaka University Shimadzu Omics Innovation Research Laboratories, Osaka University

Applicability of supercritical fluid chromatography for oligonucleotide analysis: A proof-of-concept study

J Chromatogr A 1708(2023) 464333.

  • Momoka Hayashida1,2,3
  • Risa Suzuki3
  • Shinnosuke Horie2,3,4
  • Junichi Masuda3
  • Takao Yamaguchi1
  • Satoshi Obika1
  1. 1Graduate School of Pharmaceutical Sciences, Osaka University
  2. 2Shimadzu Analytical Innovation Research Laboratories
  3. 3Shimadzu Corporation
  4. 4Shimadzu Europa GmbH

Chitosan-based coating enriched with melezitose alters primary metabolites in fresh-cut pineapple during storage

Biosci Bioeng. 2023 Nov;136(5):374-382.

  • Muhammad Maulana Malikul Ikram 1
  • Sastia Prama Putri 1 2
  • Eiichiro Fukusaki 1 2 3
  1. 1Department of Biotechnology, Graduate School of Engineering, Osaka University
  2. 2Industrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University
  3. 3Osaka University-Shimadzu Omics Innovation Research Laboratories, Osaka University

Identification of potential quality markers in Indonesia's Arabica specialty coffee using GC/MS-based metabolomics approach

Metabolomics. 2023 Oct 25;19(11):90.

  • Fitri Amalia 1
  • Tomoya Irifune 1
  • Tetsuji Takegami 1
  • Yusianto 2
  • Ucu Sumirat 2
  • Sastia Prama Putri 3 4
  • Eiichiro Fukusaki 1 5 6
  1. 1Department of Biotechnology, Graduate School of Engineering, Osaka University
  2. 2Indonesian Coffee and Cocoa Research Institute
  3. 3Department of Biotechnology, Graduate School of Engineering, Osaka University
  4. 4Industrial Biotechnology Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University
  5. 5Industrial Biotechnology Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University
  6. 6Osaka University Shimadzu Omics Innovation Research Laboratories

Improvement of ethanol and 2,3-butanediol production in Saccharomyces cerevisiae by ATP wasting

Microb Cell Fact. 2023 Oct 8;22(1):204.

  • Futa Yatabe # 1
  • Taisuke Seike # 1 2
  • Nobuyuki Okahashi 1 2 3
  • Jun Ishii 4 5
  • Fumio Matsuda 6 7 8
  1. 1Department of Bioinformatics Engineering, Graduate School of Information Science and Technology, Osaka University
  2. 2Industrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University
  3. 3Analytical Innovation Research Laboratory, Graduate School of Engineering, Osaka University Shimadzu, Osaka University
  4. 4Engineering Biology Research Center, Kobe University
  5. 5Graduate School of Science, Technology and Innovation, Kobe University
  6. 6Department of Bioinformatics Engineering, Graduate School of Information Science and Technology, Osaka University
  7. 7Industrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University
  8. 8Analytical Innovation Research Laboratory, Graduate School of Engineering, Osaka University Shimadzu, Osaka University

Lipidome and metabolome analyses reveal metabolic alterations associated with MCF-7 apoptosis upon 4-hydroxytamoxifen treatment

Sci. Rep. (2023) 13:18549

  • Kazuki Nishimoto 1
  • Nobuyuki Okahashi 1 2 3
  • Masaharu Maruyama 1
  • Yoshihiro Izumi 4
  • Kohta Nakatani 4
  • Yuki Ito 2 5
  • Junko Iida 2 5
  • Takeshi Bamba 4
  • Fumio Matsuda 1 2 3
  1. 1Department of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University
  2. 2Department of Biotechnology, Osaka University Shimadzu Analytical Innovation Research Laboratory, Graduate School of Engineering, Osaka University
  3. 3Industrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University
  4. 4Division of Metabolomics, Medical Research Center for High Depth Omics, Medical Institute of Bioregulation, Kyushu University
  5. 5Analytical and Measuring Instruments Division, Shimadzu Corporation

Comprehensive analysis of the composition of the major phospholipids during the asexual life cycle of the filamentous fungus Aspergillus nidulans

Biochim Biophys Acta Mol Cell Biol Lipids. 2023 Oct;1868(10):159379.

  • Ryo Iwama a b
  • Nobuyuki Okahashi c d
  • Tetsuki Suzawa a
  • Chuner Yang a
  • Fumio Matsuda c d
  • Hiroyuki Horiuchi a b
  1. aDepartment of Biotechnology, The University of Tokyo
  2. bCollaborative Research Institute for Innovative Microbiology, The University of Tokyo
  3. cGraduate School of Information Science and Technology, Osaka University
  4. dOsaka University Shimadzu Omics Innovation Research Laboratories, Graduate School of Engineering, Osaka University

Using Mass Spectrometry Imaging to Visualize Pesticide Accumulation and Time-Dependent Distribution in Fungicide-Coated Seeds

Mass Spectrom (Tokyo). 2023;12(1):A0132.

  • Shuichi Shimma 1 2 3
  • Hiromi Saito 1
  • Takuya Inoue 4
  • Fukumatsu Iwahashi 4
  1. 1Department of Biotechnology, Graduate School of Engineering, Osaka University
  2. 2Osaka University Shimadzu Analytical Innovation Laboratory, Osaka University
  3. 3Institute for Open and Transdisciplinary Research Initiatives, Osaka University
  4. 4Health & Crop Sciences Research Laboratory, Sumitomo Chemical Company, Ltd.

Improvement of the functional value of green soybean (edamame) using germination and tempe fermentation: A comparative metabolomics study

J Biosci Bioeng. 2023 Sep;136(3):205-212.

  • Marvin Nathanael Iman 1
  • Rafidha Irdiani 1
  • Della Rahmawati 1 4
  • Eiichiro Fukusaki 1 2 3
  • Sastia Prama Putri 1 2
  1. 1Department of Biotechnology, Graduate School of Engineering, Osaka University
  2. 2Industrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University
  3. 3Osaka University-Shimadzu Omics Innovation Research Laboratories, Osaka University
  4. 4Department of Food Technology, Faculty of Life Science and Technology, Swiss German University

Visualization of azoxystrobin penetration in wheat leaves using mass microscopy imaging

J Pestic Sci. 2023 May 20;48(2):29-34.

  • Soichiro Ikuta 1
  • Eiichiro Fukusaki 1 2 3
  • Shuichi Shimma 1 2 3
  1. 1Department of Biotechnology, Graduate School of Engineering, Osaka University.
  2. 2Osaka University Shimadzu Omics Innovation Research Laboratory, Osaka University.
  3. 3Institute for Open and Transdisciplinary Research Initiatives, Osaka University.

Solvent effects of N,N-dimethylformamide and methanol on mass spectrometry imaging by tapping-mode scanning probe electrospray ionization

Analyst. 2023 Mar 13;148(6):1275-1284.

  • Yoichi Otsuka 1 2 3
  • Nijiho 4
  • Mengze Sun 1
  • Shuichi Shimma 5
  • Osamu Urakawa 6
  • Shinichi Yamaguchi 7
  • Tomoya Kudo 7
  • Michisato Toyod 1 3
  1. 1Department of Physics, Graduate School of Science, Osaka University
  2. 2JST, PREST
  3. 3Forefront Research Center, Graduate School of Science, Osaka University
  4. 4Department of Biological Sciences, School of Science, Osaka Universit
  5. 5Department of Biotechnology, Graduate School of Engineering, Osaka University
  6. 6Department of Chemistry, Graduate School of Science, Osaka University
  7. 7Shimadzu Corporation

Lipidome variation of industrial Saccharomyces cerevisiae strains analyzed by LC-QTOF/MS-based untargeted lipidomics

J Biosci Bioeng, 135(2) 102-108

  • Shuka Komori 1
  • Nobuyuki Okahashi 1 2 3
  • Junko Iida 2 4
  • Fumio Matsuda 1 2 3
  1. 1Department of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University
  2. 2Osaka University Shimadzu Analytical Innovation Research Laboratory, Graduate School of Engineering, Osaka University
  3. 3Industrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University
  4. 4Analytical and Measuring Instruments Division, Shimadzu Corporation

Metabolite Changes in Indonesian Tempe Production from Raw Soybeans to Over-Fermented Tempe

Metabolites. 2023 Feb 17;13(2):300.

  • Mahensa Billqys Nurhayati Prativi 1,2
  • Dea Indriani Astuti 1
  • Sastia Prama Putri 1,3,4
  • Walter A. Laviña 5
  • Eiichiro Fukusaki 3,4,6
  • Pingkan Aditiawati 1,*
  1. 1School of Life Sciences and Technology, Institut Teknologi Bandung
  2. 2Research and Development Agency, West Java Provincial Government
  3. 3Department of Biotechnology, Graduate School of Engineering, Osaka University
  4. 4Industrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University
  5. 5Microbiology Division, Institute of Biological Sciences, University of the Philippines Los Baños
  6. 6Osaka University-Shimadzu Omics Innovation Research Laboratories

2022

Isotope Calculation Gadgets: A Series of Software for Isotope-Tracing Experiments in Garuda Platform

Metabolites 2022, 12(7), 646

  • Nobuyuki Okahashi 1 2 3
  • Yuki Yamada 1
  • Junko Iida 2 4
  • Fumio Matsuda 1 2 3
  1. 1Department of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University
  2. 2Department of Biotechnology, Osaka University Shimadzu Analytical Innovation Research Laboratory, Graduate School of Engineering, Osaka University
  3. 3Industrial Biotechnology Initiative Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University
  4. 4Analytical and Measuring Instruments Division, Shimadzu Corporation
Back to top