Next Industry Standard Nexis GC-2030 with HS-20 made drug substance residual solvent analysis simpler with constant flow mode

Introduction

Method transfer is no more challenge to Shimadzu new Nexis GC-2030 with HS-20 sampler for residual solvent analysis in drug substance as Nexis GC-2030 can now run in constant flow as an additional carrier gas flow mode. This enables smooth method transfer between different makes of GC. Furthermore, GC-2030 can use the constant linear velocity and constant pressure modes with multistage programing. All control modes can be used with advanced flow technologies, such as backflush, detector switching which leads to better gains in productivity. In this application, data obtained from Make A for the residual solvents analysis of drug substance Sitagleptin was compared with the data generated on Nexis GC-2030 coupled with HS-20 to ascertain repeatability and no carry over during method transfer.

December 18, 2019 GMT