Targeted Proteomics Approach for Sensitive Detection of Bovine and Porcine Gelatins in Food, Pharmaceutical Capsules and Personal Care Products

Introduction

Gelatin has been extensively utilized in food, cosmetic and pharmaceutical industries and is often manufactured from bovine and porcine materials. The use of animal-based gelatin is restricted if it is incompatible with several religious custom and personal dietary preferences which require the gelatin to be free from porcine, bovine or any animal by- products. Accurate labelling is requisite for consumers’ confidence towards the products. However, high similarity in amino acid sequences between bovine and porcine gelatins is a main challenge for differentiation of the animal sources. A targeted proteomic analysis employing sensitive LC/MS/MS platform was developed to pinpoint species-specific peptide markers for gelatin speciation.

December 6, 2019 GMT