Determination of Dexamethasone and its organic impurities content as per USP monograph UHPLC method

User Benefits

- Shimadzu Nexera XS can be effectively used for assay and organic impurities test of Dexamethasone as per the USP monograph UHPLC method - The Nexera XS easily meets with all the acceptance criteria as per the USP monograph for examethasone

Introduction

Dexamethasone (see Fig. 1) is a glucocorticoid medication used to treat rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive lung disease, croup, brain swelling, eye pain following eye surgery, and along with antibiotics in tuberculosis. It may be given by mouth, as an injection into muscle and vein, as a topical cream or ointment for the skin or as a topical ophthalmic solution to the eye. The long-term use of dexamethasone may result in thrush, bone loss, cataracts, easy bruising, or muscle weakness. Dexamethasone also has anti-inflammatory and immunosuppressant effects.

November 29, 2021 GMT