Automated support functions utilizing digital technology, such as M2M, IoT, and Artificial Intelligence (AI), that enable higher productivity and maximum reliability.
Nexera series
Ultra High Performance Liquid Chromatograph
Shimadzu has long been advancing the analytical performance of HPLC systems. At the same time, we recognize that overall efficiency depends not only on the performance of one instrument but on the management of all devices within a lab. This realization leads us to now, a time in which AI capabilities have been incorporated to allow devices to detect and resolve issues automatically. In addition, lab management has been integrated using the Internet of Things (IoT) and device networking, making it simple to review the status of instruments and optimize resource allocation.
Columns utilized in ultra high performance liquid chromatography (UHPLC) must suppress intra-column dispersion, provide excellent chromatographic separation, and support high-speed, high-separation analysis. The Shimadzu Nexflow technology* for the Nexera system minimizes the extra-column dispersion, without changing the inner diameter or length of the piping in the UHPLC system.
Building upon 40 years of experience in LC technology, the Nexera series is a family of HPLC systems that marries these AI and IoT enhancements to set new industry standards.
* This is optional for the Shimadzu Nexera system. The effectiveness differs depending on the analysis conditions. For details, check with your Shimadzu representative.
Lineup
Nexera X3/ XS/ XR/ lite
Nexera series Lineup
Features
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Allows a system to monitor and diagnose itself, handle any issues during data acquisition without user input, and automatically behave as if it were operated by an expert. -
Supports the acquisition of high quality, reproducible data regardless of an operator’s skill level for both routine and demanding applications. -
Latest Webinar
Movies
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Nexera series
- Experience New Benchmarks - The Nexera series is a family of HPLC systems that marries AI and IoT enhancements to set new industry
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Nexera series Concept Video
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Evaluating Technical Proficiency of ADRA Skin Sensitization
Evaluating Technical Proficiency of ADRA Skin
Sensitization Testing and High Speed Analysis
It can meet the standards of the proficiency assessment test and the system suitability test of the ADRA test method, which is one of the skin sensitization tests to assess the allergy of chemicals to the skin. It also allows for quick analysis. -
Important Notices for Daily Use of HPLC: 1. Ghost peak (Artifact peak)
We sometimes face minor difficulties, resulting in unsatisfactory HPLC results, even when carefully following official methods and/or well-established analytical conditions. There must be tips and know-how for improving unwanted phenomena.
| Description | Q'ty |
|---|---|
| LC-40D | 2 |
| PEEK Tube, 0.13mmIDx3000mm | 1 |
| Shodex HILICpak VG-50 4E(250 × 4.6 mm I.D., 5 μm) | 1 |
| SHIMADZU LabTotal™ for LC 1.5 mL, Glass A | 1 |
| LC LabSolutions | 1 |
| LabSolutions LC Workstation Single | 1 |
| TOOL KIT 1 | 1 |
| CORD,UC-975-N01 | 5 |
| Optical Fiber Cable Assy, Plastic, for Nexera Series | 1 |
| REGULATOR,W/FILTER | 1 |
| PEEK Male Nut | 2 |
| CBM-40 lite | 1 |
| PIPING KIT A, for HPGE ID0.3 | 1 |
| MR 180μL II | 1 |
| RESERVOIR TRAY | 1 |
| ELSD-LT III | 1 |
| CTO-40C | 1 |
| VIAL PLAT 1.5mL | 2 |
| SIL-40C | 1 |
| DGU-403 | 1 |
| Description | Q'ty |
|---|---|
| LC-40B XR | 1 |
| Mobile Phase Monitor (Contoller) | 1 |
| LC LabSolutions | 1 |
| LabSolutions LCGC,DB Multi LC-PDA | 1 |
| SYSTEM BASE KIT B | 2 |
| LOCKING PLATE | 1 |
| BELT | 1 |
| MPM Bottle Holder Kit,Eeathquake-R | 1 |
| CMD CABLE | 1 |
| Mobile Phase Monitor AC Adapter | 1 |
| Mobile Phase Monitor(bottle holder) | 2 |
| Glass Reservoir Bottle, w/Cap, 5pcs | 1 |
| SCL-40 | 1 |
| TOOL KIT | 1 |
| POWER OUTLET UNIT | 1 |
| Optical Fiber Cable Assy, Plastic, for Nexera Series, C 1 CORD,UC-975-N01 | 5 |
| PIPING KIT B, for HPGE ID0.1 | 1 |
| MR 180μL II | 1 |
| SPD-M40 | 1 |
| CTO-40C | 1 |
| VIAL PLAT 1.5mL | 2 |
| SIL-40CXR | 1 |
| DGU-403 | 1 |
| Description | Q'ty |
|---|---|
| SCL-40 | 1 |
| LC-40D XR | 1 |
| DGU-40A5 | 1 |
| LPGE UNIT | 1 |
| SIL-40 | 1 |
| CTO-40C | 1 |
| SPD-M40A | 1 |
| LC WORKSTATION | 1 |
| LC WORKSTATION LabSolutions | 1 |
| SEMI MICRO TEMP CONT CELL | 1 |
| Mixer （300 uL） | 1 |
| Description | Q'ty |
|---|---|
| SCL-40 | 1 |
| LC-40B XR | 1 |
| DGU-403 | 1 |
| SIL-40CXR | 1 |
| Vial plate 1.5mL | 1 |
| CTO-40S CN | 1 |
| SPD-M40 | 1 |
| MR 180 μL II | 1 |
| PIPING KIT B, for HPGE ID0.1 | 1 |
| Optical Fiber Cable Assy, Plastic, for Nexera Series,C | 1 |
| UC-975-N01 2.5m | 1 |
| LabSolutions LCGC,DB Multi LC-PDA | 1 |
| Description | Q'ty |
|---|---|
| SCL-40 | 1 |
| LC-40B XR | 1 |
| DGU-405 | 1 |
| SIL-40CXR | 1 |
| CTO-40S | 1 |
| SPD-M40 | 1 |
| MR 180μLⅡ | 1 |
| LC WORKSTATION | 1 |
| LC WORKSTATION Labsolution | 1 |
| Description | Q'ty |
|---|---|
| CBM-40 | 1 |
| Shim-pack SCR-102(H) | 2 |
| LC PC LabSolutions PC | 1 |
| TOOL KIT | 1 |
| CORD,UC-975-N01 | 1 |
| PEEK Male Nut | 1 |
| PEEK Tube, 0.25mmIDx3000mm | 1 |
| PEEK Tube, 0.13mmIDx3000mm | 1 |
| FITTING SET 20A | 1 |
| LabSolutions LCGC,DB Single LC | 1 |
| Reagent Kit for organic acid analysis system | 1 |
| GUARD COLUMN FOR SCR-102H | 1 |
| TUBING ASSY | 1 |
| LC-40D | 2 |
| CABLE,HFBR3600-1-021 | 1 |
| RESERVOIR TRAY | 1 |
| CDD-10Avp | 1 |
| COLUMN CALMP B8 | 2 |
| CTO-40C | 1 |
| Vial plate 1.5mL | 1 |
| SIL-40C | 1 |
| DGU-403 | 1 |
| Bottle, 250ml | 1 |
| WASHING PUMP SEAL KIT | 2 |
| Description | Q'ty |
|---|---|
| LC-40D | 2 |
| MPM Bottle Holder Kit,Eeathquake-R | 1 |
| Shim-pack Scepter C18-120 A | 1 |
| Shim-pack VP-Phenyl | 1 |
| SHIMADZU Vials, TORAST-H Glass Vial, 1.5mL | 1 |
| LC LabSolutions | 1 |
| LabSolutions LCGC,DB Single LC | 1 |
| SYSTEM BASE KIT B | 1 |
| LOCKING PLATE | 1 |
| BELT | 1 |
| CMD CABLE | 1 |
| CBM-40Lite | 1 |
| Mobile Phase Monitor AC Adapter CN | 1 |
| Mobile Phase Monitor(bottle holder) | 1 |
| Mobile Phase Monitor (Contoller) | 1 |
| Glass Reservoir Bottle, w/Cap, 5pcs | 1 |
| RESERVOIR TRAY | 1 |
| SPD-40V | 1 |
| CTO-40C | 1 |
| SIL-40C | 1 |
| DGU-403 | 1 |
| Description | Q'ty |
|---|---|
| CBM-40 | 1 |
| Bottle, 250ml | 2 |
| Shim-pack GIST-HP C18-AQ | 1 |
| SCR-102(H) | 1 |
| Shim-pack SCR-102H | 2 |
| TOOL KIT | 1 |
| FITTING SET 20A | 2 |
| CABLE,HFBR3600-1-021 | 4 |
| COLUMN CALMP B8 | 1 |
| Vial plate 1.5mL | 2 |
| WASHING PUMP SEAL KIT | 2 |
| LC-40D | 2 |
| RESERVOIR TRAY | 1 |
| LabsolutionsLCGC,Single | 1 |
| SPD-40 | 1 |
| TUBING ASSY | 1 |
| CDD-10Avp | 1 |
| CTO-40C | 1 |
| SIL-40C | 1 |
| DGU-403 | 1 |
| Description | Q'ty |
|---|---|
| LC-40D | 2 |
| SCL-40 | 1 |
| DGU-403 | 1 |
| SIL-40C | 1 |
| CTO-40C | 1 |
| ELSD-LTIII | 1 |
| Imtakt Presto FF-C18（150 mm×4.6 mmI.D.;2 μm） | 1 |
| Labtotal Vial KIT | 1 |
| MR20 μL | 1 |
| Piping kit 0.3 mm | 1 |
| Cable Assy | 1 |
| LC LabSolutions Single LC | 1 |
| REGULATOR,W/FILTER | 1 |
| Description | Q'ty |
|---|---|
| SCL-40 | 1 |
| LC-40B XR | 1 |
| DGU-403 | 1 |
| SIL-40C XR | |
| CTO-40C | 1 |
| SPD-M40 | 1 |
| CRB-40 | 1 |
| D582/F LCsolution Ver.1.25 AD | 1 |
| GLP 0.1φX2M | 1 |
| GLP 0.5φX1M | 1 |
| GLP 0.5φX5M | 1 |
| FEMALE T 1.6FT316L-0.4 | 1 |
| PEEK Male Nut, 5pcs/pack | 1 |
News / Events
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Determination of heterocyclic oxygen compounds in Citrus essential oils by Supercritical fluid chromatography-tandem mass spectrometry
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New Nexera UC Prep Semi-Preparative Supercritical Fluid Chromatography System
Semi-Preparative Supercritical Fluid Chromatography System
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New Nexera UC Supercritical Fluid Extraction / Supercritical Fluid Chromatograph
Nexera UC improves your analytical workflow by utilizing a completely new separation technology, Unified Chromatography, which unites sample separation, analysis with various separation modes, and high-sensitivity detection.
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New Nexera Prep Preparative Purification Liquid Chromatograph
The Nexera Prep Purification System provides optimal solutions for your laboratory needs.
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Shimadzu has released the Shim-pack™ SUR-Na Columns for Ligand Exchange Chromatography.
Shim-pack™ SUR-Na, a ligand exchange chromatography column, offers excellent performance by combining size exclusion mode and sodium-based ligand exchange mode to provide superior separation of sugar components. Pure water can be used for the mobile phase, resulting in less effort to prepare for the analysis.
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Efficient Method Development by automated pH Screening with LabSolutions MD
This article describes an example of using LabSolutions MD, a dedicated software for supporting method development, to automate pH screening by varying the mobile phase pH from 2.5 to 8.5 to evaluate the optimal pH level for separating 12 small-molecule drugs.
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