Using GCMS to Determine the 2,3-Butanedione, 2,3-Pentanedione, and Acetoin Content in E-liquid

User Benefits

- Users can analyze impurities in e-liquid, which will be regulated in China. - Users can analyze the content of 2,3-butanedione, 2,3-pentanedione, and acetoin in e-liquid with high sensitivity, good repeatability, and with simple sample preparation.

Introduction

A method of using a Shimadzu GCMS-QP2020 NX gas chromatograph mass spectrometer to determine the 2,3- butanedione, 2,3-pentanedione, and acetoin content in e-liquid was devised. Samples were dissolved in and adjusted to volume with ethanol, vortexed, filtered through a membrane, and then analyzed. Results of that analysis revealed that calibration curves for 2,3-butanedione, 2,3-pentanedione, and acetoin had good linearity in the range of 0.2 to 2.0 mg/L, with linear correlation coefficients greater than 0.998. The detection limit for each component was within 0.05 to 1.27 mg/kg. In the recovery test using actual samples, the recovery of each component was 75.8 to 112.5 % for a spike concentration of 6 mg/kg. This method involves simple sample preparation, offers high sensitivity and good repeatability, and can be used to determine the 2,3-butanedione, 2,3-pentanedione, and acetoin content in e-liquid.

April 5, 2022 GMT