An Ultra-high Sensitivity Analysis of 29 PFAS Compounds in Drinking Water by Direct Injection

User Benefits

- The LCMS-8065XE enables highly sensitive and accurate analysis of 29 PFAS down to less than 1 ng/L. - 29 PFAS can be analyzed in one cycle in 18 minutes without sample preconcentration. - Good recovery of target PFAS is achieved in drinking water, enabling highly accurate quantification analysis.

Introduction

PFAS (Per- and Polyfluoroalkyl Substances) are synthetic fluorinated organic compounds. More than a few thousand compounds exist, each with a varied carbon chain length, functional groups, and structural isomers. Because of its useful qualities, such as their ability to repel water and their non-stickiness, PFAS are found in a wide range of consumer and industrial products, including firefighting foams and coatings. Their high stability and persistence raise concerns about their impact on human health and the environment. In recent years, regulations and studies regarding PFAS have been increasing globally. For example, the U.S. Environmental Protection Agency (EPA) has set a Maximum Contaminant Level (MCL) of 4 ng/L for PFOA and PFOS in drinking water. To improve the analysis of PFAS, more sensitive, accurate and faster methods are needed. This application introduces the ultra-high sensitivity analysis of 29 PFAS in drinking water by direct injection using the LCMS-8065XE and addresses the demands of testing laboratories for PFAS quantification.

August 28, 2025 GMT