GPC Analysis using Integrated LC System ~Calculation of Molecular Weight Distribution for Synthetic Polymers

User Benefits

- GPC system with small footprint can be setup by adding refractive index detector (RID-20A) to Integrated LC System “i-Series LC-2070”. - LabSolutions GPC option software provides intuitive operation from creation of calibration curve to calculation of molecular weight distribution.

Introduction

GPC (gel permeation chromatography) analysis is widely used as a straightforward analytical method for confirming the molecular weight distribution of synthetic polymers. Refractive index detector, which responds to the weight of the target compounds is often used for the detection for GPC analysis. Integrated LC System “i-Series LC-2070” can be applied to GPC analysis by just configuring refractive index detector “RID-20A”, resulting in small footprint GPC system setup. The column oven can accommodate up to three 300 mm columns, which are commonly used in GPC analysis despite the compact size of LC-2070. In this article, the basic procedures from GPC analysis to data reprocessing, as well as the calculation of molecular weight distribution calculation using our workstation LabSolutions GPC option software are introduced.

September 24, 2025 GMT