Alcohol Determination of Sanitizer Gel Using Nexis GC-2060

User Benefits

- The newly developed FID on the Nexis GC-2060 provides excellent linearity for high-concentration samples. - The Nexis GC-2060 enables rapid oven heating and cooling, allowing results to be obtained quickly. - A special liner for aqueous solutions and an Xtra Life Microsyringe enable highly repeatable data acquisition.

Introduction

Methods for alcohol determination are specified in USP (United States Pharmacopeia) General Chapters <611> ALCOHOL DETERMINATION, which describes both a distillation and a gas chromatography method. In USP <611>, Method II (gas chromatography) includes a capillary column method (Method IIb). For GC analysis of samples containing a large amount of water (e.g., sanitizing ethanol), sample vaporization may become unstable, resulting in abnormal peak shapes and poor repeatability. In addition, with a standard micro-syringe for AOC, the plunger may become stiff during aspiration and dispensing of aqueous solutions, which can degrade repeatability. This article presents an example of alcohol determination in sanitizing ethanol using the Nexis GC-2060 equipped with a newly developed FID. The Nexis GC-2060 can be configured with a newly developed FID that has high sensitivity and excellent linearity. In addition, a special liner for aqueous solutions and an Xtra Life Microsyringe were used to achieve repeatable analysis.

April 7, 2026 GMT