Analysis of Inorganic Elements in Blood Using EDXRF

User Benefits

- Inorganic elements in blood can be quantified at the µg/mL level without any complicated sample pretreatment. - Qual-quantitative analysis is possible using the FP (Fundamental Parameter) method, which does not require standards. - Qual-quantitative results are obtained within 10 minutes per sample.

Introduction

Inorganic elements such as potassium, calcium, and iron are essential substances for maintaining normal metabolism and vital activities in the human body. In contrast, heavy metals poisoning can result from accidents or criminal incidents, and the causative elements are diverse. Some of these elements are highly toxic, but because they often lack specific poisoning symptoms, early identification can be difficult. Therefore, rapid analytical methods are needed. Inorganic elements are generally analyzed by ICP-AES or ICP-MS. Although these techniques allow trace-level quantitation, they require chemical pretreatment such as dilution and deproteinization, and the samples are limited to liquids. In contrast, EDX-7200 enables simple, non-destructive analysis in a short time and has sufficient sensitivity for screening purpose. This application describes quantitative analysis results for 15 elements in blood using calibration curves, and qualitative and quantitative analysis results using the FP method based on sensitivity coefficients built into the instrument. The accuracy of the quantitative values obtained by the FP method was 84–103%, demonstrating sufficient quantitative performance. Analysis can be completed within 10 minutes per sample.

August 17, 2026 GMT