Multi-omics Analysis Package

The Process Flow of Multi-omics Analysis Package

Multi-omics Analysis Package includes various data processing gadgets which connect with corresponding data analysis gadgets, providing a seamless, connected experience of a single software program. Furthermore it is designed to work in combination with various Shimadzu database, which ensures the entire process flow, from obtaining mass spectrometer measurements to data analysis, can be performed smoothly.

Data Analysis Example

Changes in metabolite levels in a cell culture medium over time were measured using a GC-MS system. Acquired data was analyzed using the Multi-omics Analysis Package and metabolite changes were visualized by displaying them on a metabolic map.

Tools for Data Analysis

The Multi-omics Analysis Package is based on software tools (called gadgets) that have been released on the GARUDA platform - an open research platform, developed by the GARUDA Alliance led by The Systems Biology Institute, Japan (SBI).

http://www.garuda-alliance.org/

Data Analysis Tools Used in the Multi-omics Analysis Package

Volcano Plot
A tool that combines a t-test (statistically significant difference) and a fold-change (Example: Difference in mean value such as 2 times or 1/2) to visualize the differences between the two groups. The Volcano Plot gadget developed by Shimadzu is included in the package.

VANTED
Tool maintained at University of Konstanz, Germany, for visualization and analysis of networks across different data sets. (GARUDA support was developed at Monash University)

Cytoscape
Bioinformatics tool developed by the Cytoscape Consortium, used to visualize metabolic pathways, to integrate gene expression profiles with related data, and so on. It is especially useful for analyzing networks and visualizing correlations.

Method Packages for Omics

Tools for Data Analysis

Smart Metabolites Database is a trademark of Shimadzu Corporation.
GARUDA is a trademark of The Systems Biology Institute.