Autosampler
Nexera Series
SIL-30AC
SIL-30AC Autosampler
The total-volume injection SIL-30AC autosampler features a pressure tolerance of 130 MPa as well as the world’s fastest sample injection (10 seconds), which dramatically reduces the total cycle time. It includes auto pretreatment and overlapping functions as standard, and an optional loop-injection method configuration to minimize delay volume. With reduction of the needle contact area, special coatings, surface treatments, and a new needle seal, the SIL-30AC reaches a new level of low carryover performance, which is especially beneficial for LCMSMS analysis. In addition, the included sample cooler features a dehumidifier function for storing samples at a constant temperature between 4°C and 40°C.
Rackchanger II and SIL-30AC Autosampler
The rackchanger unit replaces the microplates on autosampler racks to enable samples to be continuously analyzed . It allows loading up to 12 microplates inside the unit (maximum 4608 samples). Samples can be temperature-controlled with a block heating/cooling system (with dehumidifier function and 4 °C to 40 °C range) not only to refrigerated temperatures, but also to stable temperature levels near room temperature.
| Method | Variable sample injection volume and total volume direct injection |
|---|---|
| Allowable Operating Pressure | 66 MPa |
| Injection Volume Range | 0.1 µL to 50 µL (0.1 µL to 100 µL with option) |
| Number of Samples Processed | 175 (1-mL vials), 105 (1.5-mL vials, 70 for 20AC), 50 (4-mL vials), 192 (two 96-well MTP/DWP), 768 (two 384-well MTP/DWP) Besides these, ten 1.5-mL vials can be used |
| Injection Volume Precision | Max RSD 0.3 % (normally max 0.2 %: depending on specified conditions) |
| Cross-Contamination | Max 0.005 % (depending on specified conditions, without rinsing, normally max 0.0035 %) |
| Needle Rinsing | Freely settable, before or after sample injection |
| Operational Temp. Range | 4 - 35 °C |
Prominence Series
SIL-20A/20AC Autosampler
SIL-20A
The SIL-20A is a total volume injection type (direct injection) autosampler that enables high-speed injection and multi-analyte processing. Materials used in needle, valve, and other flow lines were closely considered and a needle rinsing function is provided to carefully minimize cross-contamination (carryover), which is especially useful for high-precision LC-MSMS analysis. The SIL-20AC includes a sample cooler that features a dehumidifier function for storing samples at a constant temperature between 4 °C and 40 °C.
Rack Changer
The rackchanger unit exchanges the microplates on autosampler racks to enable samples to be continuously analyzed. 12 plates can be mounted inside the main unit and stored under refrigerated conditions.
| Method | Variable sample injection volume and total volume direct injection |
|---|---|
| Injection Volume Range | 0.1 µL to 100 µL (0.1 µL to 2000 µL with option) |
| Number of Samples Processed | 175 (1-mL vials), 105 (1.5-mL vials), 50 (4-mL vials), 192 (two 96-well MTP/DWP), 768 (two 384-well MTP/DWP) *Twelve 96-well MTP/DWP in the rackchanger |
| Injection Volume Precision | Max RSD 0.3 % (under specified conditions) |
| Cross-Contamination | Max 0.005 % (naphthalene and chlorhexidine) |
| Needle Rinsing | Freely settable, before or after sample injection |
Comparison for Autosampler Selection Autosamplers can be selected according to objectives.
| Model Name | Features/Applications | Injection Volume (µL) | Number of Vials | Microplate Capacity | Main Liquid Contact Surface Materials |
|---|---|---|---|---|---|
| SIL-20A | Outstanding reproducibility and accuracy for trace volume injection. A needle rinsing function is included standard to minimize cross-contamination (carryover). It also allows high speed injection. (direct injection, specialized needle coating, and PEEK rotor) | 0.1 to 100 (max 2000) | 175 (1 mL), 105/70 (1.5 mL), 50 (4 mL) | Cools max two 96/384-well plates | PEEK, (SS) |
Manual Injectors
7725/7725i,
8125 (semi-micro),
9725/9725i (PEEK)
3725i (Preparative)
News / Events
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Cosmetics and Personal Care Products
The environment surrounding cosmetics and personal care products is changing. In addition to serving the original aesthetic purpose, cosmetics are required to be environmentally friendly and impart no adverse effects on animals.
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Shimadzu has released the Catechin Analysis Kit
The National Agriculture and Food Research Organization (NARO) and Shimadzu are studying fast, convenient, and accurate methods for analyzing the functional components in foods for purposes of data analysis and social implementation.
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Shimadzu has updated the LabSolutions MD
LabSolutions MD uses an “Analytical Quality by Design” (AQbD) approach for achieving efficient method development by designing analysis methods based on science and risk.
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Biodegradable Plastics
In order to reduce plastic waste, the development of eco-friendly alternative materials is being promoted. As an alternative, biomass plastics and biodegradable plastics are becoming more widely available. Biodegradable Plastics are plastics that are decomposed into low-molecular compounds by microorganisms in the environment. So they break down easily in nature, which is an opposite characteristic of petroleum-based plastics.
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Shimadzu has released the Nexera lite inert
Nexera lite inert is a robust HPLC system that eliminates the risk of corrosion by high-salt mobile phases and sample adsorption onto metal surfaces. It improves the data quality of protein analysis in biological samples with superior reproducibility, without any special considerations for stable and long-term use.
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Shimadzu has updated the i-Series, High Performance Liquid Chromatograph
Amid increasing calls for improved work efficiency and a more flexible working style, ideas of LC analysis are changing. The time has come for an HPLC that delivers rugged, reliable results with less frequent interaction by the analyst. The new, integrated i-Series LC system maintains the excellent performance of its predecessor while addressing the need for automation efficiency.