Nexera Prep
Preparative Purification Liquid Chromatograph

Nexera Prep
The Nexera Prep systems are designed for fast and efficient purification of target compounds. It helps to streamline the purification process and purity check analysis. The Nexera Prep system is equipped with a simple user interface which allows easy setting of multiple fractionation parameters, analytical conditions, and reporting. Shimadzu offers preparative LC systems for all laboratory scales, from microgram-scale to gram-scale purification. This system also features Open Solution™ – a tailored software for open access systems that greatly simplifies complex workflows.
- Easy optimization of preparative parameters and scale up
Fractionation simulation for rapid setup of collection logic Column line-up for scale-up from analytical to preparative - Time- and energy-saving by automation of the purification workflow
Collection of target components at high purity by automated desalting - Expandable to suit the sample/fraction number and volume
Choose from a wide range of options for recovery scale and analytical detection Problems are resolved simply, to accommodate a variety of needs.
Streamline and Simplify Establishing the Conditions for Preparative Work
Using the Nexera Prep system saves on labor when scaling up from the development of analytical conditions to the conditions for preparative work.
Preparative Work for Target Components at High Purity Levels and High Concentrations
The Nexera UFPLC™, Ultra Fast Preparative and Purification Liquid Chromatograph, significantly reduces the cost and labor involved in preparative purification. Additionally, the system not only performs purification of target components, but can also recover impurities with high yield, enabling direct impurity analysis.
Streamline and Simplify Establishing the Conditions for Preparative Work
With LH-40 and FRC-40 able to perform signal-based logic and collection on up to four signal channels, not having a chromophore is not a limitation. Nexera Prep can use LCMS, RID, and ELSD to detect and/or identify targets for purification.
Increased Efficiency from Preparative Analysis Setup to Data Processing
Open Solution™ is open access software that not only streamlines preparative purification operations, but also supports multi-user operation of preparative systems.
Prep Solution is straightforward to operate even for inexperienced users, because the number of parameter settings characteristic of preparative work has been reduced to the utmost.
Increased Efficiency from Preparative Analysis Setup to Data Processing
By repeatedly cycling the sample through the column, the target component can be resolved and recovered from coeluting species or impurities without the need for longer or multiple columns.
Excellent System Expandability
The solvent delivery unit and fraction collector can be selected to suit the recovery volume. Sample introduction and reinjection options cover a wide range of uses. Additionally, the Shim-pack Scepter™ columns feature excellent scalability from analytical to preparative separations with a variety of phases for different applications.
Nexera, Open Solution, Shim-pack Scepter, LabSolutions and Purication Solution are trademarks of Shimadzu Corporation or its affiliated companies in Japan and/or other countries.
Features
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Using the Nexera™ Prep system saves on labor when scaling up from the development of analytical conditions to the conditions for preparative work.
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The Shimadzu UFPLC, Ultra Fast Preparative and Purification Liquid Chromatograph significantly reduces the cost and labor involved in preparative purification. Additionally, the system not only performs purification of target components, but can also recover impurities with high yield enabling direct impurity analysis.
-
With LH-40 and FRC-40 able to perform signal-based logic and collection on up to four signal channels, not having a chromophore is not a limitation. Nexera Prep can use LCMS, RID, and ELSD to detect and/or identify targets for purification.
-
Open Solution is open access software that not only streamlines preparative purification operations, but also supports multi-user operation of preparative systems.
-
By repeatedly cycling the sample through the column, the target component can be resolved and recovered from coeluting species or impurities without the need for longer or multiple columns.
-
The solvent delivery unit and fraction collector can be selected to suit the recovery volume. Sample introduction and reinjection options cover a wide range of uses. Additionally, the Shim-pack™ Scepter columns feature excellent scalability from analytical to preparative separations with a variety of phases for different applications.
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News / Events
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New Tips & Tricks is available, Automated Dilution and Preparation of Standard and Sample Solutions for Analysis
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Shimadzu Corporation has released LabSolutions Detect, a software with AI Functionality to support Anomaly Detection for Liquid Chromatographs (LC).
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New Technical Report is available, A sustainable analytical approach for detecting extra virgin olive oil adulteration using Nexera™ UC
In this study, a fast, simple and green methodology was optimized to detect intentionally adulterated extra virgin olive oil EVOO with cheaper seed oils at different levels by means of subcritical fluid chromatography (subFC) with UV detection, followed by statistical analysis.
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Shimadzu has released the new integrated LC system, i-Series.
The new i-Series integrated LC: Sustainable design. Reliable results. Uncompromising performance.
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Core-shell Column: Analysis Basics Now Available.
Discover easy-to-understand insights into the fundamentals of analysis.
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Ecology simulation for HPLC System is now available.
Replacing your Shimadzu HPLC (High-Performance Liquid Chromatographs) with a newer model can save on running costs and reduce CO2 emissions.