Nexera Prep
Preparative Purification Liquid Chromatograph

Nexera Prep
- Easy optimization of preparative parameters and scale up
Fractionation simulation for rapid setup of collection logic Column line-up for scale-up from analytical to preparative - Time- and energy-saving by automation of the purification workflow
Collection of target components at high purity by automated desalting - Expandable to suit the sample/fraction number and volume
Choose from a wide range of options for recovery scale and analytical detection Problems are resolved simply, to accommodate a variety of needs.
Nexera, Open Solution, Shim-pack Scepter, LabSolutions and Purication Solution are trademarks of Shimadzu Corporation or its affiliated companies in Japan and/or other countries.
Features
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Using the Nexera™ Prep system saves on labor when scaling up from the development of analytical conditions to the conditions for preparative work.
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The Shimadzu UFPLC, Ultra Fast Preparative and Purification Liquid Chromatograph significantly reduces the cost and labor involved in preparative purification. Additionally, the system not only performs purification of target components, but can also recover impurities with high yield enabling direct impurity analysis.
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With LH-40 and FRC-40 able to perform signal-based logic and collection on up to four signal channels, not having a chromophore is not a limitation. Nexera Prep can use LCMS, RID, and ELSD to detect and/or identify targets for purification.
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Open Solution is open access software that not only streamlines preparative purification operations, but also supports multi-user operation of preparative systems.
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By repeatedly cycling the sample through the column, the target component can be resolved and recovered from coeluting species or impurities without the need for longer or multiple columns.
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The solvent delivery unit and fraction collector can be selected to suit the recovery volume. Sample introduction and reinjection options cover a wide range of uses. Additionally, the Shim-pack™ Scepter columns feature excellent scalability from analytical to preparative separations with a variety of phases for different applications.
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News / Events
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The HIC-ESP is a new anion suppressor ion chromatograph with built-in electrodialytic suppressor, boasting the same low carryover and excellent injection precision characteristic of Shimadzu HPLCs to bring you highly-reliable results. The newly developed anion suppressor prevents peak spreading and achieves high sensitivity, providing stable functionality even over long periods of use.
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Multiple Analytical Techniques For Carotenoid Analysis In Capsicum Cultivars
Carotenoids and their derivatives are versatile isoprenoids based on a C40 tetraterpenoid skeleton and play a vital role in plants and animals, but, due to their high variability in the chemical structures, isomerization, poor stability and lack of commercially available standards, their identication in real samples is a challenging task.
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New Method Development System
LabSolutions™ MD improves method development efficiency by taking an Analytical Quality by Design (AQbD) approach. This software efficiently develops highly reliable analysis methods by configuring mobile phases, columns, and other parameters using an analysis function that automatically generates analysis schedules with the experimental design method and a data analysis function that plots a design space and predicted chromatogram.
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An Improvement in Preparative SFC Efficiency Utilizing Online SFE-SFC System as a “Solid Autosampler”
Preparative SFC is a groundbreaking separation and purification technology. It has a number of advantages in comparison to preparative LC including simplified posttreatment, shorter analysis times, and different separation selectivity. With preparative SFC, the injection of large sample volumes is often required in order to increase the recovered amount.
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SFC Analytical Condition Parameters is available.
The approach for the SFC analytical condition development process is basically the same as for determining analytical conditions for HPLC.
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Latest issue of Shimadzu Journal, featuring Forensics / Toxicology, has come out.
This issue focuses on "Forensics / Toxicology", an area where science and technology are particularly important and needed. It starts with two customer interviews.