Using the Nexera™ Prep system saves on labor when scaling up from the development of analytical conditions to the conditions for preparative work.
Nexera Prep
Preparative Purification Liquid Chromatograph
Nexera Prep
- Easy optimization of preparative parameters and scale up
Fractionation simulation for rapid setup of collection logic Column line-up for scale-up from analytical to preparative - Time- and energy-saving by automation of the purification workflow
Collection of target components at high purity by automated desalting - Expandable to suit the sample/fraction number and volume
Choose from a wide range of options for recovery scale and analytical detection Problems are resolved simply, to accommodate a variety of needs.
Features
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The Shimadzu UFPLC, Ultra Fast Preparative and Purification Liquid Chromatograph significantly reduces the cost and labor involved in preparative purification. Additionally, the system not only performs purification of target components, but can also recover impurities with high yield enabling direct impurity analysis. -
With LH-40 and FRC-40 able to perform signal-based logic and collection on up to four signal channels, not having a chromophore is not a limitation. Nexera Prep can use LCMS, RID, and ELSD to detect and/or identify targets for purification.
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By repeatedly cycling the sample through the column, the target component can be resolved and recovered from coeluting species or impurities without the need for longer or multiple columns. -
The solvent delivery unit and fraction collector can be selected to suit the recovery volume.
Additionally, the Shim-pack™ Scepter features excellent scalability from analysis to preparative work, and the preparation of a variety of components is supported by an ample lineup.
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News / Events
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Shimadzu has released the Shim-pack™ SUR-Na Columns for Ligand Exchange Chromatography.
Shim-pack™ SUR-Na, a ligand exchange chromatography column, offers excellent performance by combining size exclusion mode and sodium-based ligand exchange mode to provide superior separation of sugar components. Pure water can be used for the mobile phase, resulting in less effort to prepare for the analysis.
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Efficient Method Development by automated pH Screening with LabSolutions MD
This article describes an example of using LabSolutions MD, a dedicated software for supporting method development, to automate pH screening by varying the mobile phase pH from 2.5 to 8.5 to evaluate the optimal pH level for separating 12 small-molecule drugs.
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Oligonucleotide Therapeutics Solution Guide is now available
Oligonucleotide therapeutics are nucleic acid polymers generally comprised of a few to several dozen bases (including modified bases) linked together. They are produced by chemical synthesis and act directly on organisms without being translated into proteins.
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Cosmetics and Personal Care Products
The environment surrounding cosmetics and personal care products is changing. In addition to serving the original aesthetic purpose, cosmetics are required to be environmentally friendly and impart no adverse effects on animals.
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Shimadzu has released the Catechin Analysis Kit
The National Agriculture and Food Research Organization (NARO) and Shimadzu are studying fast, convenient, and accurate methods for analyzing the functional components in foods for purposes of data analysis and social implementation.
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Shimadzu has updated the LabSolutions MD
LabSolutions MD uses an “Analytical Quality by Design” (AQbD) approach for achieving efficient method development by designing analysis methods based on science and risk.
Sustainability initiatives
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2 Zero hunger
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3 Good health and well-being