Water soluble vitamins contain many highly polar basic components, which are known to exhibit weak retention in the reverse-phase mode.
Shim-pack MAqC-ODS
HPLC Column
Shim-pack MAqC-ODS I reversed-phase columns are packed with a silica gel containing metal and added octadecylsilyl group. In addition to the hydrophobic characteristics of the ODS, the metal content also provides cation-exchange effects. This increases the retention of basic compounds. Therefore, this allows use with only a buffer solution as the mobile phase for analyses that previously required using an ion pair reagent and enables using gradient elution. These characteristics are especially beneficial for analyzing water soluble vitamins and pharmaceuticals that contain a large amount of basic compounds.
Features
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Many pharmaceuticals are basic compounds. The majority of impurities in pharmaceuticals, such as unreacted ingredients, by-products, and decomposition products... -
News / Events
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Cosmetics and Personal Care Products
The environment surrounding cosmetics and personal care products is changing. In addition to serving the original aesthetic purpose, cosmetics are required to be environmentally friendly and impart no adverse effects on animals.
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Shimadzu has released the Catechin Analysis Kit
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Shimadzu has updated the LabSolutions MD
LabSolutions MD uses an “Analytical Quality by Design” (AQbD) approach for achieving efficient method development by designing analysis methods based on science and risk.
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Biodegradable Plastics
In order to reduce plastic waste, the development of eco-friendly alternative materials is being promoted. As an alternative, biomass plastics and biodegradable plastics are becoming more widely available. Biodegradable Plastics are plastics that are decomposed into low-molecular compounds by microorganisms in the environment. So they break down easily in nature, which is an opposite characteristic of petroleum-based plastics.
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Shimadzu has released the Nexera lite inert
Nexera lite inert is a robust HPLC system that eliminates the risk of corrosion by high-salt mobile phases and sample adsorption onto metal surfaces. It improves the data quality of protein analysis in biological samples with superior reproducibility, without any special considerations for stable and long-term use.
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Shimadzu has updated the i-Series, High Performance Liquid Chromatograph
Amid increasing calls for improved work efficiency and a more flexible working style, ideas of LC analysis are changing. The time has come for an HPLC that delivers rugged, reliable results with less frequent interaction by the analyst. The new, integrated i-Series LC system maintains the excellent performance of its predecessor while addressing the need for automation efficiency.