Descriptions Notes
Shimadzu LC control license 1 license only
Shimadzu LC Driver for Waters Empower First Year Support Plan Single (for 1 system) For either personal or enterprise use
Shimadzu LC Driver for Waters Empower First Year Support Plan Multi (for 4 systems) For either personal or enterprise use
  • * If using an Empower enterprise system, Shimadzu’s dedicated LAC/E32 server is required.
  • * Up to 4 Shimadzu LC/GC systems can be controlled from one computer or LAC/E32 intake server. However, if 1 or 2 PDAs are connected, this reduces the number of GCs/LCs that can be connected by 1 or 2 respectively.
  • * To control a Shimadzu LC, a Shimadzu LC control license is required in addition to a LAC/E32 system control license.

Supported devices


Unit Model Name
i-Series LC-2030
LC-2030C LT
LC-2030C 3D
LC-2040C LT
LC-2040C MT
LC-2040C 3D
LC-2040C 3D MT
LC-2030C LT+
LC-2030C 3D+
LC-2040C LT+
LC-2040C MT+
LC-2040C 3D+
LC-2040C 3D MT+
LC-2050C 3D
LC-2050C LT
LC-2060C 3D
LC-2060C 3D MT
External Detector RF-20A, RF-20AXS
AD Input Board
SPD-M30A *3
SPD-30AM *3
SPD-M40 *4
Mobile Phase Flow Line Switching Valve FCV-11AL, FCV-11ALS
High-Pressure Flow-Line Switching Valve FCV-14AH, FCV-34AH

Nexera series (Ver. 1.30) 

Unit Model Name Minimum required
ROM Version
System Controller SCL-40, CBM-40, CBM-40lite 1.50
Mobile Phase Monitor MPM-40 1.02
Pump LC-40D, LC-40D XR, LC-40B XR, LC-40D XS, LC-40D X3, LC-40B X3 1.02
LC-40D XSi 1.07 *1
LC-20AB 2.02
Autosampler SIL-40, SIL-40C, SIL-40 XR, SIL-40C XR, SIL-40C XS, SIL-40C X3 1.05 *2
SIL-40C XSi 1.10 *1,*2
SIL-30ACMP 3.21
Plate Changer 1.04 *2
Column Oven CTO-40C, CTO-40S 1.00
CTO-30A 3.11
Detector SPD-40, SPD-40V 1.02
RID-20A 2.04
RF-20A, RF-20AXS 2.02
CDD-10Avp 5.10
Analog Input board -
SPD-M40 2.01
SPD-M30A 4.04
Mobile Phase Flow Line Switching Valve LPGE Unit, FCV-11AL, FCV-11ALS, Recycling valve for UV detector -
High-Pressure Flow Line Switching Valve FCV-36AH -
FCV-0206, FCV-0607, FCV-0206H, FCV-0607H, FCV-0206H3, FCV-0607H3, FCV-0206H2i, FCV-0607H2i - *3
FCV-DR 1.02
  • *1: To control this instrument, it is necessary to update the ROM version of the system controller to Ver. 1.60 or later.
    *2: If the ROM version of the autosampler is updated to Ver. 1.08 or later, it is also necessary to update the ROM version of Plate Changer to Ver. 1.08 or later.
    *3: The high-pressure flow line switching valves can only be connected to the column oven.
  • [Note]
  • The "Nexera series" diver does not support other modules such as LC-30AD.

Nexera/Prominence (Ver. 4.42) 

Unit Model Name Minimum required
ROM Version
System Controller CBM-20A, CBM-20Alite 3.50
Pump LC-30AD 3.21
LC-20AD 2.11
LC-20ADXR 1.23
LC-20AT 2.01
LC-20AB 2.02
LC-20Ai 1.00
Column Oven CTO-30A 3.11
CTO-20A, CTO-20AC 2.10
CTO-10AS VP 5.28
Autosampler SIL-30AC 3.20
SIL-30ACFV 3.20
SIL-20A, SIL-20AC (including HT and UFLC models) 1.28
SIL-20AXR, SIL-20ACXR 1.28
Rack Changer II 2.00
Rack Changer, Rack Changer C 1.11
Sub Controller Sub Controller VP 5.22
Option Box VP
Detector SPD-20A, SPD-20AV 2.03
RF-20A, RF-20AXS 2.02
RF-10AXL 3.33
RID-20A 1.02
CDD-10Asp, CDD-10Avp 5.10
SPD-M20A 2.03
SPD-M30A 4.02
SPD-30AM 4.01
AD Input Board (PC-55N) -
Mobile Phase Flow Line Switching Valve FCV-10AL / FCV-10ALvp / FCV-11AL / FCV-11ALS / FCV-15AL /Switching Valve
4-port solenoid valve built into LC-20AD / LC-20AT / LC30-AD
High-Pressure Flow-Line Switching Valve FCV-12AH / FCV-13AL / FCV-14AH -
  FCV-12AH / FCV-14H / FCV-32AH built into CTO-20A / CTO-20AC / CTO-30A


  • * 4 systems maximum with no PDA or 3 systems with single PDA or 2 systems with 2 PDA (per LAC/E).
  • * CBM-20A lite will not support analogue data acquisition. Please use CBM-20A with a PC-55N AD board if analogue signal is acquired.
  • * If you use Empower 3 FR4 or later, please update the driver to Ver 4.41 or later to control LC-2010.
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