Liquid Chromatograph with online Sample Preparation
In LC-MS, there are various factors which may preclude the applicability of HPLC with MS analysis, including the interference associated with non-volatile buffers often used in HPLC. Therefore, tedious procedures are adopted, in which separation and collection is conducted by HPLC, and after desalting and other processing, MS measurement is performed.
Co-Sense for LC-MS automates the entire process of separating and purifying the target compounds from the sample, including the processes of purifying, concentrating and desalting. This eliminates the need to select HPLC mobile phases to accommodate subsequent measurement using LC-MS.
Shimadzu has released ELSD-LT III Evaporative Light Scattering Detector for HPLC.
The evaporative light scattering detector (ELSD) is a general-purpose universal detector that can even detect components with no UV absorption, such as carbohydrates, lipids, surfactants, and synthetic polymers.
Shimadzu has released the Microsampling Device, MSW2™ Type Udck™
For Research Use Only. Not for use in diagnostic procedures.
Application Note: "Analysis of Pharmaceuticals' Impurity - Regulations and Analysis for Carcinogenic Substances -"
Shimadzu has released Shim-pack MC PLONAS Series.
Shim-pack MC PLONAS 2.7 μm columns reduce the back pressure yet maintain the performance of a sub 2 μm fully porous particle column. The pressure limit is 40 MPa.
Application Note: "Various Analysis Techniques for Organic Acids and Examples of Their Application"
TORAST-H Vial Series
LC/MS(/MS) has been introduced in many fields as an indispensable separation analysis method thanks to its high sensitivity and selectivity.
