All sample processing, from introduction, separation and concentration of target compounds, desalting and solvent replacement, to transfer to the LC-MS, has been completely automated.
Co-Sense for LC-MS
Liquid Chromatograph with online Sample Preparation
In LC-MS, there are various factors which may preclude the applicability of HPLC with MS analysis, including the interference associated with non-volatile buffers often used in HPLC. Therefore, tedious procedures are adopted, in which separation and collection is conducted by HPLC, and after desalting and other processing, MS measurement is performed.
Co-Sense for LC-MS automates the entire process of separating and purifying the target compounds from the sample, including the processes of purifying, concentrating and desalting. This eliminates the need to select HPLC mobile phases to accommodate subsequent measurement using LC-MS.
Features
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Fully Automated Sample Processing
All sample processing, from introduction, separation and concentration of target compounds, desalting and solvent replacement, to transfer to the LC-MS, has been completely automated.
News / Events
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Recommended Reading: AI, Automation, and the Future of Drug Discovery Description
In this Drug Discovery News interview, Raymond Wong of Shimadzu UK shares insights into how AI-enabled workflows, connected data, and laboratory automation are helping accelerate pharmaceutical research and development.
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Shimadzu has released the Nexera X4 Ultra High Performance Liquid Chromatograph.
Expanding on technologies cultivated with previous Nexera series models, the next-generation Nexera X4 ultra high performance liquid chromatograph (UHPLC) achieves an incomparable level of analytical performance. The lowest degree of peak broadening* in the industry results in ultra-sharp peaks and outstanding separation performance while cutting-edge fluid control technology provides exceptional solvent delivery consistency, even for fast analysis under ultra-high-pressure conditions, and highly reliable results. Engineered with precision, the high-end Nexera X4 UHPLC offers new value for all laboratories that demand maximum performance.
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Nexera IC Ion Chromatograph has been released.
The Nexera IC ion chromatograph combines a compact footprint with uncompromising performance, enabling anyone to perform analysis effortlessly and efficiently.
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PL-40, Automation-Compatible Plate Loader for LC/LC-MS Systems has been released
The PL-40 solves for LC/LC-MS automation, it seamlessly loads plates of pretreated samples into an LC/LC-MS system, enabling a fully automated workflow, from pretreatment to analysis.
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New Technical Report is available, Optimization of Supercritical Fluid Extraction Parameters for Vitamins D2, D3, and K1 from Pharmaceutical Preparations
New Technical Report is available, Optimization of Supercritical Fluid Extraction Parameters for Vitamins D2, D3, and K1 from Pharmaceutical Preparations
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New Tips & Tricks is available, Automated Dilution and Preparation of Standard and Sample Solutions for Analysis