i-Series Method Transfer System
Enables Both HPLC and UHPLC Analysis
The i-Series Method Transfer System (MT system) enables both conventional analysis via its high compatibility with existing LC systems and rapid analysis via high-speed methods.In pharmaceutical development, a single integrated system allows process synthesis screening analysis for synthetic substances in the UHPLC flow line, and impurity content identification in the HPLC flow line.
Analysis results from LC systems in the same laboratory may differ, even with the same method, due to differences in the system delay volumes of these systems. The i-Series MT system demonstrates outstanding reproducibility between various LC systems with different system delay volumes, simplifying method transfer between instruments.
Further more, with the i-Series MT system the process of migrating from UHPLC to HPLC or from HPLC to UHPLC can be accomplished using a single system.
The i-Series MT system is based on the same user-friendly i-Series, but maximizes performance and reliability for migrating and transferring customer methods.
A single integrated system allows analyses in two flow lines with UHPLC and HPLC delay volumes. In addition to simplifying the transfer of analytical methods for customers using HPLC, it can also streamline the process of converting customers’ analytical methods from HPLC to higher-speed UHPLC.
The newly developed Analytical Condition Transfer and Optimization (ACTO) function incorporated in LabSolutions™ allows users to transfer injection timings matched to differences in system volumes between instruments, without editing the concentration gradient programs in existing methods.
Transfer Methods with a Single Button Operation—ACTO Function
Core Technologies That Provide a Solid Foundation for Analysis
News / Events
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Semi-Preparative Supercritical Fluid Chromatography System
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Shim-pack™ SUR-Na, a ligand exchange chromatography column, offers excellent performance by combining size exclusion mode and sodium-based ligand exchange mode to provide superior separation of sugar components. Pure water can be used for the mobile phase, resulting in less effort to prepare for the analysis.
Efficient Method Development by automated pH Screening with LabSolutions MD
This article describes an example of using LabSolutions MD, a dedicated software for supporting method development, to automate pH screening by varying the mobile phase pH from 2.5 to 8.5 to evaluate the optimal pH level for separating 12 small-molecule drugs.
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