Nexera FV - Features
Ultra High Performance Liquid Chromatograph for Online Dissolution Testing
Provides Labor Savings and Faster Speeds in Dissolution Testing
System Configuration for Online Dissolution Testing
With the Nexera FV, the dissolution tester and the autosampler are connected online, so everything is automated from sampling to dilution to data acquisition and analysis. There is no manual dispensing of samples, ensuring reliable results.
Flow Vials Provide Automated of Dissolution Testing
Dissolution medium from the dissolution tester flows directly into flow vials loaded into the autosampler. A bubble suppression design has been adopted for these flow vials, enabling high-accuracy sampling of dissolution media. Depending on the dissolution tester used, 8 or 12 flow vials can be loaded.
Sufficient to Quickly Dissolving Samples Tests
Two Analysis Modes Promote Faster Dissolution Testing
Direct Injection Analysis Mode: Exclusively with the Nexera System
If the analysis of the dissolution sample set finishes before the next sampling time, the medium can be injected directly from the flow vial connected to the dissolution tester, for use in analysis.
Fraction Analysis Mode: For Confirmation of Dissolution Profiles Equivalent with UV Spectrophotometers
This analysis mode is used for tests with very short dissolution sampling intervals. Up to 768 samples can be fractionated. This mode is also effective when dissolution quantities are large and dilution is required. Sampling intervals as short as 5 minutes are realistic.
Reliable Performance Expands the Range of Choices
Compatible with High-Concentration Samples Requiring Dilution
One System Plays Two Roles, Significantly Improving the Throughput of the Testing Lab
The Nexera FV is a multipurpose system for on-line dissolution testing and high-efficiency UHPLC analysis, such as compound screening.
Provides High Cost Effectiveness in Testing Thanks to Consumables with a Long Operating Life
A special septum is used for the flow vial that receives the dissolution medium. It boasts a better degree of adherence after needle penetration in comparison to a regular septum, and can be used for 100 continuous injections without leaking. This greatly reduces maintenance, enabling continuous testing.
Substantial Improvements in Work Scheduling
Special Software Makes Testing Preparation More Efficient
DT-Solution Software Supports the Creation and Implementation of Test Schedules
With dissolution tests, one of the most labor-intensive processes is establishing a batch schedule for the test. The custom DT-Solution software eases the burden. The user can configure all the required information in a single window. Then, click a single button to automatically generate a batch schedule in LabSolutions so that testing can smoothly start.
Rapid Confirmation of Test Results and Automatic Generation of Reports
The browser function built into LabSolutions is convenient for assessing changes in the chromatogram over time. Multiple data set can be displayed simultaneously in a single window, so the data can be compared at a glance. In addition, the creation of reports on the test results can be completely automated with the multi-data report function. When the test finishes, a result table, pivot graphs, and test pass/fail judgments for each component are created automatically, so the test results can be rapidly confirmed.
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Nexera FV - Ultra High Performance Liquid Chromatograph for Online Dissolution Testing [ PDF / 3.43MB ]