Nexera lite inert - Features
Improved Data Reliability by Preventing System Corrosion by Halogenic Salt
Aggregates of antibody drugs show immunogenicity and cause a decrease in purification efficiency and production. Therefore, an aggregation test is one of the most critical evaluations when manufacturing biopharmaceuticals and controlling their quality. However, a metal-free LC system is required for good repeatability over a long time due to high-concentration, salt-containing mobile phases such as Sodium chloride. With no metal material in the flow path, Nexera lite inert provides stable aggregate assay results with good repeatability.
- Monoclonal IgG antibody aggregate analysis by size exclusion chromatographyte
- Corrosion resistance test results of pump heads
Superior Retention Time Stability by Highly Accurate Solvent Delivery
Thanks to the outstanding flow-rate stability, the Nexera lite inert provides excellent retention time repeatability.
Real-Time Monitoring of Mobile Phase pH
In ion exchange or size exclusion chromatography, the pH of the mobile phase sometimes affects the separation of compounds. The pH Monitor, pHM-40, continuously monitors and records the pH of the mobile phase. The pH and detector chromatograms are saved within the same data file and can be overlapped, ensuring efficient data traceability.